Incidence, prevention, and treatment of parenteral nutrition–associated cholestasis and intestinal failure–associated liver disease in infants and children: a systematic …

G Lauriti, A Zani, R Aufieri, M Cananzi… - Journal of parenteral …, 2014 - Wiley Online Library
Background: Cholestasis is a significant life‐threatening complication in children on
parenteral nutrition (PN). Strategies to prevent/treat PN‐associated cholestasis (PNAC) and …

Lipids in the intensive care unit: recommendations from the ESPEN Expert Group

PC Calder, M Adolph, NE Deutz, T Grau, JK Innes… - Clinical Nutrition, 2018 - Elsevier
This article summarizes the presentations given at an ESPEN Workshop on “Lipids in the
ICU” held in Tel Aviv, Israel in November 2014 and subsequent discussions and updates …

ASPEN clinical guidelines: support of pediatric patients with intestinal failure at risk of parenteral nutrition–associated liver disease

PW Wales, N Allen, P Worthington… - Journal of Parenteral …, 2014 - Wiley Online Library
Background: Children with severe intestinal failure and prolonged dependence on
parenteral nutrition are susceptible to the development of parenteral nutrition–associated …

ASPEN position paper: clinical role for alternative intravenous fat emulsions

VW Vanek, DL Seidner, P Allen… - Nutrition in Clinical …, 2012 - Wiley Online Library
The currently available, standard soybean oil (SO)–based intravenous fat emulsions (IVFEs)
meet the needs of most parenteral nutrition (PN) patients. There are alternative oil‐based fat …

Intestinal failure-associated liver disease

L Pironi, AS Sasdelli - Clinics in liver disease, 2019 - liver.theclinics.com
Intravenous supplementation (IVS) of parenteral nutrition (PN) admixtures and/or fluid and
electrolyte solutions is the primary treatment of intestinal failure (IF), defined as “the …

[HTML][HTML] Omega-3 fatty acids in modern parenteral nutrition: a review of the current evidence

S Klek - Journal of clinical medicine, 2016 - mdpi.com
Intravenous lipid emulsions are an essential component of parenteral nutrition regimens.
Originally employed as an efficient non-glucose energy source to reduce the adverse effects …

Parenteral nutrition–associated cholestasis: an American Pediatric Surgical Association outcomes and clinical trials committee systematic review

SJ Rangel, CM Calkins, RA Cowles… - Journal of Pediatric …, 2012 - Elsevier
OBJECTIVE: The aim of this study was to review evidence-based data addressing key
clinical questions regarding parenteral nutrition–associated cholestasis (PNAC) and …

Neonates with short bowel syndrome: an optimistic future for parenteral nutrition independence

EM Fallon, PD Mitchell, D Nehra, AK Potemkin… - JAMA …, 2014 - jamanetwork.com
Importance The introduction of hepatoprotective strategies and multidisciplinary
management has significantly improved the outcome of neonates with short bowel …

High rates of resolution of cholestasis in parenteral nutrition-associated liver disease with fish oil-based lipid emulsion monotherapy

MH Premkumar, BA Carter, KM Hawthorne, K King… - The Journal of …, 2013 - Elsevier
OBJECTIVE: To determine factors leading to resolution of cholestasis in patients with
parenteral nutrition-associated liver disease treated with fish oil-based lipid emulsion …

Redefining essential fatty acids in the era of novel intravenous lipid emulsions

L Anez-Bustillos, DT Dao, GL Fell, MA Baker, KM Gura… - Clinical nutrition, 2018 - Elsevier
The essentiality of fatty acids was determined by the Burrs in the 1920s. It is commonly
accepted that provision of linoleic (LA) and alpha-linolenic acids (ALA) prevents and …