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Pathways and genes involved in steroid hormone metabolism in male pigs: A review and update
A Robic, T Faraut, A Prunier - The Journal of steroid biochemistry and …, 2014 - Elsevier
This paper reviews state-of-the-art knowledge on steroid biosynthesis pathways in the pig
and provides an updated characterization of the porcine genes involved in these pathways …
and provides an updated characterization of the porcine genes involved in these pathways …
Comparative cytotoxic effects and possible mechanisms of deoxynivalenol, zearalenone and T-2 toxin exposure to porcine leydig cells in vitro
L Sun, J Dai, J Xu, J Yang, D Zhang - Toxins, 2022 - mdpi.com
Mycotoxins such as zearalenone (ZEN), deoxynivalenol (DON) and T-2 toxin (T-2) are the
most poisonous biological toxins in food pollution. Mycotoxin contaminations are a global …
most poisonous biological toxins in food pollution. Mycotoxin contaminations are a global …
Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line
KEM Ahmed, HG Frøysa, OA Karlsen, N Blaser… - Chemosphere, 2019 - Elsevier
The presence of environmental pollutants in our ecosystem may impose harmful health
effects to wildlife and humans. Several of these toxic chemicals have a potential to interfere …
effects to wildlife and humans. Several of these toxic chemicals have a potential to interfere …
Effects of novel brominated flame retardants on steroidogenesis in primary porcine testicular cells
Brominated flame retardants are chemicals with fire quenching properties which are
extensively used in manufacturing. Historically, less regulated use of legacy brominated …
extensively used in manufacturing. Historically, less regulated use of legacy brominated …
Sirtuin 1-mediated autophagy regulates testosterone synthesis in Leydig cells of piglets
Y Zhang, L Yu, Y He, C Liu, MM Abouelfetouh, S Ju… - Theriogenology, 2024 - Elsevier
Testosterone is secreted by Leydig cells (LCs), which play an important physiological role in
preserving male secondary sex characteristics, protecting male reproductive function, and …
preserving male secondary sex characteristics, protecting male reproductive function, and …
An investigation of the endocrine disrupting potential of enniatin B using in vitro bioassays
Evidence that some of the fungal metabolites present in food and feed may act as potential
endocrine disruptors is increasing. Enniatin B (ENN B) is among the emerging Fusarium …
endocrine disruptors is increasing. Enniatin B (ENN B) is among the emerging Fusarium …
Exploration of steroidogenesis‐related genes in testes, ovaries, adrenals, liver and adipose tissue in pigs
A Robic, K Feve, I Louveau, J Riquet… - Animal science …, 2016 - Wiley Online Library
To explore the metabolism of steroids in the pig species, a qualitative PCR analysis was
performed for the main transcript of 27 genes involved in steroid metabolism. We compared …
performed for the main transcript of 27 genes involved in steroid metabolism. We compared …
Developmental changes in the role of gonadotropin-inhibitory hormone (GnIH) and its receptors in the reproductive axis of male **aomeishan pigs
L Zheng, J Su, R Fang, M **, Z Lei, Y Hou, Z Ma… - Animal Reproduction …, 2015 - Elsevier
Abstract Gonadotropin-inhibitory hormone (GnIH), a key regulator of vertebrate reproduction,
was identified in the Japanese quail in 2000, and RFamide-related peptide-3 (RFRP-3) was …
was identified in the Japanese quail in 2000, and RFamide-related peptide-3 (RFRP-3) was …
Pig StAR: mRNA expression and alternative splicing in testis and Leydig cells, and association analyses with testicular morphology traits
Y Zhang, Y Cui, X Zhang, Y Wang, J Gao, T Yu, X Lv… - Theriogenology, 2018 - Elsevier
Steroidogenic acute regulatory protein (StAR), primarily expressed in Leydig cells (LCs) in
the mammalian testes, is essential for testosterone biosynthesis and male fertility. However …
the mammalian testes, is essential for testosterone biosynthesis and male fertility. However …
Pig Hsd17b3: Alternative splice variants expression, insertion/deletion (indel) in promoter region and their associations with male reproductive traits
M Chen, W Yang, N Liu, X Zhang, W Dong… - The Journal of steroid …, 2019 - Elsevier
Abstract Hydroxysteroid 17-Beta Dehydrogenase 3 (Hsd17b3), primarily expressed in
Leydig cells (LCs) of the mammalian testes, is essential for testosterone biosynthesis and …
Leydig cells (LCs) of the mammalian testes, is essential for testosterone biosynthesis and …