Migraine is a disabling neurological disorder, diagnosis of which is based on clinical criteria.
A shortcoming of these criteria is that they do not fully capture the heterogeneity of migraine …

Plaguing humans for more than two millennia, manifest on every continent studied, and with
more than one billion patients having an attack in any year, migraine stands as the sixth …

The understanding of migraine pathophysiology is advancing rapidly. Improved
characterisation and diagnosis of its clinical features have led to the view of migraine as a …

Understanding the mechanisms of migraine remains challenging as migraine is not a static
disorder, and even in its episodic form migraine remains an “evolutive” chronic condition …

Background Migraine is a highly prevalent primary headache disorder. Despite a high
burden of disease, key disease mechanisms are not entirely understood. Functional …

Migraine headache, a prevalent and intricate neurovascular disease, presents significant
challenges in its clinical identification. Existing techniques that use subjective pain intensity …

Aim To provide an overview of mechanisms underlying craniofacial pain; to highlight
peripheral and central adaptations that may promote chronification of pain in craniofacial …

Chronic pain is an endemic problem involving both peripheral and brain pathophysiology.
Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have …

Introduction Migraine with aura (MwA) is a neurological condition manifested in moderate to
severe headaches associated with transient visual and somatosensory symptoms, as well …

Objective To identify and validate an fMRI-based neural marker for migraine without aura
(MwoA) and to examine its association with treatment response. Methods We conducted …