Enzymes fold into three-dimensional structures to distribute amino acid residues for
catalysis, which inspired the supramolecular approach to construct enzyme-mimicking …

G-quadruplex/hemin (G4/hemin) DNAzymes are biosensing systems, but their application
remains limited by an overall low activity and a rather high level of unwarranted background …

Chimeric peptide-DNAzyme (CPDzyme) is a novel artificial peroxidase that relies on the
covalent assembly of DNA, peptides, and an enzyme cofactor in a single scaffold. An …

Dimeric G-quadruplex (G4)/Hemin has been employed to expand the catalytic repertoire of
nucleic acid. Herein, we aim to understand the effect of NH4+ ions on the catalytic behavior …

The nature, composition, and topology of the active sites of both natural and artificial
enzymes are key determinants of their catalytic performance. While interesting structural …

The G-quadruplex (GQ) formed by guanine-rich DNA strands exhibits superior thermal
stability and electric properties, which have generated substantial interest in applying GQ …

Abstract G-quadruplex (G4)-hemin complexes are a convenient peroxidase mimicking
DNAzyme for utilization in biosensing and analytical applications. Although dispersive …

Hemin/G-quadruplex (hG4) complexes are frequently used as artificial peroxidase-like
enzymatic systems (termed G4 DNAzymes) in many biosensing applications, in spite of a …

The catalytic cycle of a peroxidase-mimicking heme–DNAzyme involves an iron (IV) oxo
porphyrin π-cation radical intermediate known as compound I formed through heterolytic O …

Nanomaterials excel in mimicking the structure and function of natural enzymes while being
far more interesting in terms of structural stability, functional versatility, recyclability, and …