Is there any evidence of premature, accentuated and accelerated aging effects on neurocognition in people living with HIV? A systematic review

HL Aung, M Aghvinian, H Gouse, RN Robbins… - AIDS and Behavior, 2021 - Springer
Despite evidence of premature, accentuated and accelerated aging for some age-related
conditions such as cardiovascular diseases in people living with HIV (PLHIV), the evidence …

Differentiating HIV-associated neurocognitive disorders from Alzheimer's disease: an emerging issue in geriatric NeuroHIV

B Milanini, V Valcour - Current HIV/AIDS Reports, 2017 - Springer
Abstract Purpose of Review The purpose of this review was to examine characteristics that
may distinguish HIV-associated neurocognitive disorder (HAND) from early Alzheimer's …

HIV-1 Tat alters neuronal autophagy by modulating autophagosome fusion to the lysosome: implications for HIV-associated neurocognitive disorders

J Fields, W Dumaop, S Elueteri, S Campos… - Journal of …, 2015 - jneurosci.org
Antiretroviral therapy has increased the life span of HIV+ individuals; however, HIV-
associated neurocognitive disorder (HAND) occurrence is increasing in aging HIV patients …

Accelerated aging of selective brain structures in human immunodeficiency virus infection: a controlled, longitudinal magnetic resonance imaging study

A Pfefferbaum, DA Rogosa, MJ Rosenbloom… - Neurobiology of …, 2014 - Elsevier
Advances in treatment have transformed human immunodeficiency virus (HIV) infection from
an inexorable march to severe morbidity and premature death to a manageable chronic …

Pathogenesis of age-related HIV neurodegeneration

M Mackiewicz, C Overk, CL Achim, E Masliah - Journal of neurovirology, 2019 - Springer
People over the age of 50 are the fastest growing segment of the HIV-infected population in
the USA. Although antiretroviral therapy has remarkable success controlling the systemic …

Effects of HIV and combination antiretroviral therapy on cortico-striatal functional connectivity

M Ortega, MR Brier, BM Ances - Aids, 2015 - journals.lww.com
Objective: Determine whether HIV and combination antiretroviral therapy (cART) affect
resting-state functional connectivity (rs-fc) between the striatum and the cortical regions …

Impact of HIV and aging on neuropsychological function

LA Wendelken, V Valcour - Journal of neurovirology, 2012 - Springer
Cognitive efficiency decreases with age, and advancing age is the leading risk factor for
most neurodegenerative disorders that result in dementia. In HIV infection, risk for cognitive …

Epidemiology of dementia among the elderly in Sub‐Saharan Africa

OO Olayinka, NN Mbuyi - International Journal of Alzheimer's …, 2014 - Wiley Online Library
Objectives. To review epidemiologic studies on the prevalence, incidence, and risk factors of
dementia in sub‐Saharan Africa (SSA). Methods. A MEDLINE search (from January 1992 to …

Successful cognitive aging in persons living with HIV infection

L Malaspina, SP Woods, DJ Moore, C Depp… - Journal of …, 2011 - Springer
The number of older adults living with human immunodeficiency virus (HIV) infection is
growing and this subpopulation of the epidemic is at heightened risk for a variety of poor …

Accelerated and accentuated neurocognitive aging in HIV infection

DP Sheppard, JE Iudicello, EE Morgan, R Kamat… - Journal of …, 2017 - Springer
There is debate as to whether the neurocognitive changes associated with HIV infection
represent an acceleration of the typical aging process or more simply reflect a greater …