Metabolism refers to a series of orderly chemical reactions used to maintain life activities in
organisms. In healthy individuals, metabolism remains within a normal range. However …

In clinical treatment, two or more drugs (ie drug combination) are simultaneously or
successively used for therapy with the purpose of primarily enhancing the therapeutic …

The carcinogenicity of drugs can have a serious impact on human health, so carcinogenicity
testing of new compounds is very necessary before being put on the market. Currently, many …

Early prediction and detection enable reduced transmission of human diseases and provide
healthcare professionals ample time to make subsequent diagnoses and treatment …

Background: Based on increasing evidence, microRNAs (miRNAs) play significant roles in
various complex human diseases. Therefore, identifying the disease-related miRNAs could …

Recent studies have revealed that long noncoding RNAs (lncRNAs) are closely linked to
several human diseases, providing new opportunities for their use in detection and therapy …

Non-alcoholic steatohepatitis (NASH) is a hepatocyte inflammation based on hepatocellular
steatosis, yet there is no effective drug treatment. Atherosclerosis (AS) is caused by lipid …

Potential miRNA–disease associations (MDA) play an important role in the discovery of
complex human disease etiology. Therefore, MDA prediction is an attractive research topic …

Motivation A large number of studies have shown that circular RNA (circRNA) affects
biological processes by competitively binding miRNA, providing a new perspective for the …

MicroRNAs (miRNAs) are an important class of non-coding RNAs that play an essential role
in the occurrence and development of various diseases. Identifying the potential miRNA …