Targeting drugs to tumours using cell membrane-coated nanoparticles

RH Fang, W Gao, L Zhang - Nature Reviews Clinical Oncology, 2023 - nature.com
Traditional cancer therapeutics, such as chemotherapies, are often limited by their non-
specific nature, causing harm to non-malignant tissues. Over the past several decades …

Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Microenvironment-driven sequential ferroptosis, photodynamic therapy, and chemotherapy for targeted breast cancer therapy by a cancer-cell-membrane-coated …

WL Pan, Y Tan, W Meng, NH Huang, YB Zhao, ZQ Yu… - Biomaterials, 2022 - Elsevier
Designing and develo** nanomedicine based on the tumor microenvironment (TME) for
effective cancer treatment is highly desirable. In this work, polyvinyl pyrrolidone (PVP) …

A modular approach to enhancing cell membrane-coated nanoparticle functionality using genetic engineering

N Krishnan, Y Jiang, J Zhou, A Mohapatra… - Nature …, 2024 - nature.com
Since their initial development, cell membrane-coated nanoparticles (CNPs) have become
increasingly popular in the biomedical field. Despite their inherent versatility and ability to …

Recent progress in targeted delivery vectors based on biomimetic nanoparticles

L Chen, W Hong, W Ren, T Xu, Z Qian… - Signal transduction and …, 2021 - nature.com
Over the past decades, great interest has been given to biomimetic nanoparticles (BNPs)
since the rise of targeted drug delivery systems and biomimetic nanotechnology. Biological …

Tumor–antigen activated dendritic cell membrane-coated biomimetic nanoparticles with orchestrating immune responses promote therapeutic efficacy against glioma

X Ma, L Kuang, Y Yin, L Tang, Y Zhang, Q Fan… - ACS …, 2023 - ACS Publications
Immunotherapy has had a profound positive effect on certain types of cancer but has not
improved the outcomes of glioma because of the blood–brain barrier (BBB) and …

Biosynthesized gold nanoparticles that activate Toll-like receptors and elicit localized light-converting hyperthermia for pleiotropic tumor immunoregulation

H Qin, Y Chen, Z Wang, N Li, Q Sun, Y Lin… - Nature …, 2023 - nature.com
Manipulating the tumor immune contexture towards a more active state can result in better
therapeutic outcomes. Here we describe an easily accessible bacterial biomineralization …

[HTML][HTML] Cell membrane coated-nanoparticles for cancer immunotherapy

Y Zeng, S Li, S Zhang, L Wang, H Yuan, F Hu - Acta Pharmaceutica Sinica …, 2022 - Elsevier
Cancer immunotherapy can effectively inhibit cancer progression by activating the
autoimmune system, with low toxicity and high effectiveness. Some of cancer …

A polymer multicellular nanoengager for synergistic NIR‐II photothermal immunotherapy

C Xu, Y Jiang, Y Han, K Pu, R Zhang - Advanced Materials, 2021 - Wiley Online Library
Cell‐membrane‐coated nanoparticles (CCNPs) that integrate the biophysiological
advantages of cell membranes with the multifunctionalities of synthetic materials hold great …

Genetically engineered cell membrane–coated nanoparticles for targeted delivery of dexamethasone to inflamed lungs

JH Park, Y Jiang, J Zhou, H Gong, A Mohapatra… - Science …, 2021 - science.org
As numerous diseases are associated with increased local inflammation, directing drugs to
the inflamed sites can be a powerful therapeutic strategy. One of the common characteristics …