Endothelial Angpt2 Promotes Adipocyte Progenitor Cells Maturation to Increase Visceral Adipose Tissue Accumulation

X Yi, J Ling, Y Tang, J Cai, S Zhu… - … Research and Reviews, 2025 - Wiley Online Library
Aims Visceral adipose tissue (VAT) accumulation is essential for the occurrence and
development of obesity and related metabolic diseases. Currently, the specific mechanism …

Adipose tissue-selective ablation of ADAM10 results in divergent metabolic phenotypes following long-term dietary manipulation

L Marino, B Ni, JS Farrar, JC Lownik, JV Pearce… - Adipocyte, 2024 - Taylor & Francis
ABSTRACT A Disintegrin And Metalloproteinase domain-containing protein 10 (ADAM10),
is involved in several metabolic and inflammatory pathways. We speculated that ADAM10 …

[HTML][HTML] Cross-ancestry analysis identifies genes associated with obesity risk and protection

D Banerjee, S Girirajan - medRxiv, 2024 - pmc.ncbi.nlm.nih.gov
Gene discoveries in obesity have largely been based on European cohorts, leading to an
ancestral bias, that limits their generalizability across populations. We performed a gene …