The calcium–iron connection in ferroptosis-mediated neuronal death

S Gleitze, A Paula-Lima, MT Núñez… - Free Radical Biology and …, 2021 - Elsevier
Iron, through its participation in oxidation/reduction processes, is essential for the
physiological function of biological systems. In the brain, iron is involved in the development …

Environmental metal exposure, neurodevelopment, and the role of iron status: a review

S Schildroth, K Kordas, JA Bauer, RO Wright… - Current Environmental …, 2022 - Springer
Abstract Purpose of Review Exposure to environmental metals, like lead (Pb), manganese
(Mn), and methylmercury (Me-Hg), has consistently been implicated in neurodevelopmental …

Prenatal influences on postnatal neuroplasticity: Integrating DOHaD and sensitive/critical period frameworks to understand biological embedding in early development

ET Margolis, LJ Gabard‐Durnam - Infancy, 2025 - Wiley Online Library
Early environments can have significant and lasting effects on brain, body, and behavior
across the lifecourse. Here, we address current research efforts to understand how …

Prognostic performance of hematological and serum iron and metabolite indices for detection of early iron deficiency induced metabolic brain dysfunction in infant …

BJ Sandri, J Kim, GR Lubach, EF Lock… - The Journal of …, 2024 - Elsevier
Background The current pediatric practice of monitoring for infantile iron deficiency (ID) via
hemoglobin (Hgb) screening at one y of age does not identify preanemic ID nor protect …

Multiomic profiling of iron-deficient infant monkeys reveals alterations in neurologically important biochemicals in serum and cerebrospinal fluid before the onset of …

BJ Sandri, J Kim, GR Lubach, EF Lock… - American Journal …, 2022 - journals.physiology.org
The effects of iron deficiency (ID) during infancy extend beyond the hematologic
compartment and include short-and long-term adverse effects on many tissues including the …

[HTML][HTML] Reticulocyte hemoglobin equivalent has comparable predictive accuracy as conventional serum iron indices for predicting iron deficiency and anemia in a …

RB Rao, GR Lubach, KM Ennis-Czerniak, EF Lock… - The Journal of …, 2023 - Elsevier
Background Infantile iron deficiency (ID) causes anemia and compromises
neurodevelopment. Current screening relies on hemoglobin (Hgb) determination at 1 year of …

Biomarkers of Brain Dysfunction in Perinatal Iron Deficiency

RB Rao - Nutrients, 2024 - mdpi.com
Iron deficiency in the fetal and neonatal period (perinatal iron deficiency) bodes poorly for
neurodevelopment. Given its common occurrence and the negative impact on brain …

Diagnosing Anemia in Neonates: An Evidence-Based Approach

RD Christensen, TM Bahr, SM Tweddell… - …, 2023 - publications.aap.org
It is important for clinicians who render neonatal care to precisely and reproducibly diagnose
anemia; however, confusion arises from various definitions. For the simplicity and …

[HTML][HTML] Iron deficiency in newborn infants: global rewards for recognizing and treating this silent malady

RD Christensen, TM Bahr, DM Ward - Newborn (Clarksville, Md.), 2022 - ncbi.nlm.nih.gov
Saving lives of babies who would otherwise die is a magnificent aim. However, insuring that
survivors have full functionality, the best possible health, and maximal potential intellect …

Administering Supplemental Iron and Erythropoiesis-Stimulating Agents to Infants Born Preterm: What Do We Need to Build Consensus?

RD Christensen, TM Bahr… - The Journal of …, 2025 - pubmed.ncbi.nlm.nih.gov
Administering Supplemental Iron and Erythropoiesis-Stimulating Agents to Infants Born
Preterm: What Do We Need to Build Consensus? Administering Supplemental Iron and …