Pathophysiological mechanisms of atrial fibrillation: a translational appraisal
Atrial fibrillation (AF) is an arrhythmia that can occur as the result of numerous different
pathophysiological processes in the atria. Some aspects of the morphological and …
pathophysiological processes in the atria. Some aspects of the morphological and …
Computational modeling of the human atrial anatomy and electrophysiology
This review article gives a comprehensive survey of the progress made in computational
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
Modeling cardiac muscle fibers in ventricular and atrial electrophysiology simulations
Since myocardial fibers drive the electric signal propagation throughout the myocardium,
accurately modeling their arrangement is essential for simulating heart electrophysiology …
accurately modeling their arrangement is essential for simulating heart electrophysiology …
Radiofrequency catheter ablation of chronic atrial fibrillation guided by complex electrograms
H Oral, A Chugh, E Good, A Wimmer, S Dey… - Circulation, 2007 - Am Heart Assoc
Background—Radiofrequency catheter ablation of atrial fibrillation (AF) guided by complex
fractionated atrial electrograms has been reported to eliminate AF in a large proportion of …
fractionated atrial electrograms has been reported to eliminate AF in a large proportion of …
A randomized assessment of the incremental role of ablation of complex fractionated atrial electrograms after antral pulmonary vein isolation for long-lasting persistent …
H Oral, A Chugh, K Yoshida, JF Sarrazin… - Journal of the American …, 2009 - jacc.org
Objectives: This study sought to determine whether ablation of complex fractionated atrial
electrograms (CFAEs) after antral pulmonary vein isolation (APVI) further improves the …
electrograms (CFAEs) after antral pulmonary vein isolation (APVI) further improves the …
Genesis of complex fractionated atrial electrograms in zones of slow conduction: a computer model of microfibrosis
V Jacquemet, CS Henriquez - Heart rhythm, 2009 - Elsevier
BACKGROUND: Complex fractionated atrial electrograms are used as potential targets for
catheter ablation therapy of atrial fibrillation. Although fibrosis has been associated with the …
catheter ablation therapy of atrial fibrillation. Although fibrosis has been associated with the …
Image‐based models of cardiac structure in health and disease
Computational approaches to investigating the electromechanics of healthy and diseased
hearts are becoming essential for the comprehensive understanding of cardiac function. In …
hearts are becoming essential for the comprehensive understanding of cardiac function. In …
A three-dimensional human atrial model with fiber orientation. Electrograms and arrhythmic activation patterns relationship
The most common sustained cardiac arrhythmias in humans are atrial tachyarrhythmias,
mainly atrial fibrillation. Areas of complex fractionated atrial electrograms and high dominant …
mainly atrial fibrillation. Areas of complex fractionated atrial electrograms and high dominant …
Effects of electrical and structural remodeling on atrial fibrillation maintenance: a simulation study
T Krogh-Madsen, GW Abbott… - PLoS computational …, 2012 - journals.plos.org
Atrial fibrillation, a common cardiac arrhythmia, often progresses unfavourably: in patients
with long-term atrial fibrillation, fibrillatory episodes are typically of increased duration and …
with long-term atrial fibrillation, fibrillatory episodes are typically of increased duration and …
Mechanism underlying initiation of paroxysmal atrial flutter/atrial fibrillation by ectopic foci: a simulation study
Background—The mechanisms underlying paroxysmal atrial flutter/atrial fibrillation initiation
by ectopic foci from various locations are unclear. Methods and Results—We used parallel …
by ectopic foci from various locations are unclear. Methods and Results—We used parallel …