Bacillus species in soil as a natural resource for plant health and nutrition

AK Saxena, M Kumar, H Chakdar… - Journal of applied …, 2020 - academic.oup.com
The genus Bacillus is one of the predominant bacterial genera found in soil, and several
species of this genus have been reported from diverse ecological niches. Endowed with …

Potential biotechnological strategies for the cleanup of heavy metals and metalloids

KA Mosa, I Saadoun, K Kumar, M Helmy… - Frontiers in plant …, 2016 - frontiersin.org
Global mechanization, urbanization, and various natural processes have led to the
increased release of toxic compounds into the biosphere. These hazardous toxic pollutants …

De novo design and engineering of non-ribosomal peptide synthetases

KAJ Bozhüyük, F Fleischhacker, A Linck, F Wesche… - Nature …, 2018 - nature.com
Peptides derived from non-ribosomal peptide synthetases (NRPSs) represent an important
class of pharmaceutically relevant drugs. Methods to generate novel non-ribosomal …

[HTML][HTML] The secondary metabolite bioinformatics portal: computational tools to facilitate synthetic biology of secondary metabolite production

T Weber, HU Kim - Synthetic and Systems Biotechnology, 2016 - Elsevier
Natural products are among the most important sources of lead molecules for drug
discovery. With the development of affordable whole-genome sequencing technologies and …

Norine: Update of the nonribosomal peptide resource

A Flissi, E Ricart, C Campart, M Chevalier… - Nucleic acids …, 2020 - academic.oup.com
Norine, the unique resource dedicated to nonribosomal peptides (NRPs), is now updated
with a new pipeline to automate massive sourcing and enhance annotation. External …

Exploration and genome mining of natural products from marine Streptomyces

Z Yang, J He, X Wei, J Ju, J Ma - Applied microbiology and biotechnology, 2020 - Springer
Marine Streptomyces sp. are an important source of bioactive compounds owing to their
unique habitats and metabolic pathways. Whole-genome sequencing and bioinformatics …

Microbial lipopeptide production and purification bioprocesses, current progress and future challenges

F Coutte, D Lecouturier, K Dimitrov… - Biotechnology …, 2017 - Wiley Online Library
Lipopeoptides are amphiphilic compounds combining interesting physicochemical
properties and biological activities. Due to their high foaming capacity in aerated bioreactor …

Discovery strategies of bioactive compounds synthesized by nonribosomal peptide synthetases and type-I polyketide synthases derived from marine microbiomes

GD Amoutzias, A Chaliotis, D Mossialos - Marine drugs, 2016 - mdpi.com
Considering that 70% of our planet's surface is covered by oceans, it is likely that
undiscovered biodiversity is still enormous. A large portion of marine biodiversity consists of …

High-throughput optimization of medium components and culture conditions for the efficient production of a lipopeptide pseudofactin by Pseudomonas fluorescens …

P Biniarz, F Coutte, F Gancel, M Łukaszewicz - Microbial cell factories, 2018 - Springer
Background Lipopeptides are a promising group of surface-active compounds of microbial
origin (biosurfactants). These diverse molecules are produced mainly by Bacillus and …

Genetic Potential of the Biocontrol Agent Pseudomonas brassicacearum (Formerly P. trivialis) 3Re2-7 Unraveled by Genome Sequencing and Mining, Comparative …

J Nelkner, G Torres Tejerizo, J Hassa, TW Lin, J Witte… - Genes, 2019 - mdpi.com
The genus Pseudomonas comprises many known plant-associated microbes with plant
growth promotion and disease suppression properties. Genome-based studies allow the …