Neurofilaments: neurobiological foundations for biomarker applications

AR Gafson, NR Barthélemy, P Bomont, RO Carare… - Brain, 2020 - academic.oup.com
Interest in neurofilaments has risen sharply in recent years with recognition of their potential
as biomarkers of brain injury or neurodegeneration in CSF and blood. This is in the context …

Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration

RL Schnaar, R Gerardy-Schahn… - Physiological …, 2014 - journals.physiology.org
Every cell in nature carries a rich surface coat of glycans, its glycocalyx, which constitutes
the cell's interface with its environment. In eukaryotes, the glycocalyx is composed of …

The polygenic architecture of schizophrenia—rethinking pathogenesis and nosology

OB Smeland, O Frei, AM Dale… - Nature Reviews …, 2020 - nature.com
Schizophrenia is a severe psychiatric disorder with considerable morbidity and mortality.
Although the past two decades have seen limited improvement in the treatment of …

Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study

P Lichtenstein, BH Yip, C Björk, Y Pawitan, TD Cannon… - The Lancet, 2009 - thelancet.com
Background Whether schizophrenia and bipolar disorder are the clinical outcomes of
discrete or shared causative processes is much debated in psychiatry. We aimed to assess …

Common variants conferring risk of schizophrenia

H Stefansson, RA Ophoff, S Steinberg, OA Andreassen… - Nature, 2009 - nature.com
Schizophrenia is a complex disorder, caused by both genetic and environmental factors and
their interactions. Research on pathogenesis has traditionally focused on neurotransmitter …

[KSIĄŻKA][B] Behavioral genetics

R Plomin - 2008 - books.google.com
Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …

Genetics of schizophrenia: overview of methods, findings and limitations

MG Henriksen, J Nordgaard… - Frontiers in human …, 2017 - frontiersin.org
Genetics constitute a crucial risk factor to schizophrenia. In the last decade, molecular
genetic research has produced novel findings, infusing optimism about discovering the …

[HTML][HTML] The dual hit hypothesis of schizophrenia: Evidence from animal models

CGJ Guerrin, J Doorduin, IE Sommer… - … & Biobehavioral Reviews, 2021 - Elsevier
Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

PJ Harrison, DR Weinberger - Molecular psychiatry, 2005 - nature.com
This review critically summarizes the neuropathology and genetics of schizophrenia, the
relationship between them, and speculates on their functional convergence. The …

The neurodevelopmental hypothesis of schizophrenia, revisited

SH Fatemi, TD Folsom - Schizophrenia bulletin, 2009 - academic.oup.com
While multiple theories have been put forth regarding the origin of schizophrenia, by far the
vast majority of evidence points to the neurodevelopmental model in which developmental …