Developments in next-generation sequencing technologies have driven the clinical
application of diagnostic tests that interrogate the whole genome, which offer the chance to …

Background While the methods for conducting health economics research in general are
improving, current guidelines provide limited guidance regarding resource use …

Health economists regularly elicit quantitative preference data from samples of patients and
the general public [1–4]. Quantitative preference data, such as estimates of tradeoffs and …

There is growing interest in extending the evaluative space of the quality-adjusted life-year
framework beyond health. Using a critical interpretive synthesis approach, the objective was …

Background Genomic information could help to reduce the morbidity effects of inappropriate
treatment decisions in many disease areas, in particular cancer. However, evidence of the …

Purpose Economic evaluations of health technologies traditionally aim to maximize
population health outcomes measured by using quality-adjusted life-years (QALYs). Non …

The supermarket environment impacts the healthiness of food purchased and consumed.
Shelf tags that alert customers to healthier packaged products can improve the healthiness …

Genetic disorders are clinically diverse and genetically heterogeneous, and are traditionally
diagnosed based on an iterative phenotype-guided genetic assessment. However, such …

Background Eczema, synonymous with atopic eczema or atopic dermatitis, is a chronic skin
disease that has a similar impact on health-related quality of life as other chronic diseases …

Cost-benefit analysis (CBA) is the root of Health Economics and is based on the welfare
theory. CBA is the broadest economic evaluation (EE) method that assesses all benefits and …