A brief history of organoids
C Corrò, L Novellasdemunt… - American Journal of …, 2020 - journals.physiology.org
In vitro cell cultures are crucial research tools for modeling human development and
diseases. Although the conventional monolayer cell cultures have been widely used in the …
diseases. Although the conventional monolayer cell cultures have been widely used in the …
[HTML][HTML] AI-enabled organoids: construction, analysis, and application
L Bai, Y Wu, G Li, W Zhang, H Zhang, J Su - Bioactive Materials, 2024 - Elsevier
Organoids, miniature and simplified in vitro model systems that mimic the structure and
function of organs, have attracted considerable interest due to their promising applications in …
function of organs, have attracted considerable interest due to their promising applications in …
Causes and consequences of snake venom variation
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …
species. This variability has serious consequences for the management of the world's 1.8 …
Somatic cell-derived organoids as prototypes of human epithelial tissues and diseases
M Fujii, T Sato - Nature Materials, 2021 - nature.com
Recent progress in our understanding of the regulation of epithelial tissue stem cells has
allowed us to exploit their abilities and instruct them to self-organize into tissue-mimicking …
allowed us to exploit their abilities and instruct them to self-organize into tissue-mimicking …
[HTML][HTML] Organoids to model liver disease
S Nuciforo, MH Heim - JHEP Reports, 2021 - Elsevier
The organoid model represents a major breakthrough in cell biology that has revolutionised
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …
biomedical research. Organoids are 3D physiological in vitro structures that recapitulate …
Global Literature Analysis of Organoid and Organ‐on‐Chip Research
Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …
physiological, or pathological states of tissues and organs. These technologies are widely …
Hallmarks of stemness in mammalian tissues
All adult tissues experience wear and tear. Most tissues can compensate for cell loss
through the activity of resident stem cells. Although the cellular maintenance strategies vary …
through the activity of resident stem cells. Although the cellular maintenance strategies vary …
[HTML][HTML] Future regenerative medicine developments and their therapeutic applications
Although the currently available pharmacological assays can cure most pathological
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
disorders, they have limited therapeutic value in relieving certain disorders like myocardial …
Culture and analysis of kidney tubuloids and perfused tubuloid cells-on-a-chip
L Gijzen, FA Yousef Yengej, F Schutgens… - Nature protocols, 2021 - nature.com
Advanced in vitro kidney models are of great importance to the study of renal physiology and
disease. Kidney tubuloids can be established from primary cells derived from adult kidney …
disease. Kidney tubuloids can be established from primary cells derived from adult kidney …
Cancer research using organoid technology
K Kretzschmar - Journal of Molecular Medicine, 2021 - Springer
Organoid technology has rapidly transformed basic biomedical research and contributed to
significant discoveries in the last decade. With the application of protocols to generate …
significant discoveries in the last decade. With the application of protocols to generate …