[PDF][PDF] Hydrotropy: Recent Advancements in Enhancement of Drug Solubility and Formulation Development

AD Khan, M Tabish, R Kaushik, V Saxena… - Int. J. Drug Deliv …, 2021 - academia.edu
Solubility can be defined as the phenomenon of dissolving a solute in a solvent to prepare a
homogenous system. It is essential to get a required drug concentration in plasma to get a …

[PDF][PDF] Simultaneous UV-spectrophotometric determination and validation of diclofenac sodium and rabeprazole sodium using hydrotropic agents in its tablet dosage …

R Gunji, RR Nadendla, VS Ponnuru - International Journal of Drug …, 2012 - researchgate.net
A novel, simple, safe, sensitive, and economical method of spectrophotometric estimation in
UV region has been developed using 5M urea solution as hydrotropic solubilizing agent for …

Ecofriendly spectrophotometric estimation of tinidazole in tablets using lignocaine hydrochloride as a hydrotropic solubilizing agent

RK Maheshwari, MS Rajput… - Asian Journal of …, 2009 - asiapharmaceutics.info
Anovel, safe and sensitive method of spectrophotometric estimation in the ultraviolet region
has been developed using1M lignocaine hydrochloride (an economic drug) as a hydrotropic …

Enhancement of solubility of poorly water soluble drugs diclofenac sodium by mixed solvency approach

MA Khan - Research Journal of Pharmaceutical Dosage Forms …, 2013 - indianjournals.com
Enhancement of solubility is one of the difficult tasks which become challenges in
formulation development of orally administered drug with poor aqueous solubility. Poor …

[PDF][PDF] Simple titrimetric method to estimate ketoprofen in bulk using mixed hydrotropy

RK Maheshwari, S Sharma, N Rai… - Journal of Pharmacy …, 2010 - researchgate.net
The present investigation illustrates the application of mixed hydrotropy. The enhancement
in the solubility of ketoprofen in a mixed hydrotropoic solution containing 30% urea and 30 …

Analysis of bulk sample of salicylic acid by application of hydrotropic solubilization method

RK Maheshwari, V Chavada… - Indian journal of …, 2008 - pmc.ncbi.nlm.nih.gov
In the present investigation, the poorly water-soluble drug, salicylic acid has been
solubilized using 0.5 M ibuprofen sodium and 2.0 M sodium salicylate solution as …

Green Analytical Techniques Using Hydrotropy, Mixed Hydrotropy, and Mixed Solvency

AS Mundada, DD Patil… - Sustainable Approaches …, 2023 - Wiley Online Library
The dominance of searching for water‐soluble drugs in drug discovery has radically
amplified the obstacles. Although poorly soluble drugs signify a class of active …

[PDF][PDF] New spectrophotometric determination of hydrochlorothiazide in tablets using mixed hydrotropic solubilization technique

RK Maheshwari, MS Rajput, S Sharma… - Der Pharmacia …, 2010 - researchgate.net
The present investigation illustrates the application of mixed hydrotropy. A novel, safe and
sensitive method of spectrophotometric estimation in the ultraviolet region has been …

An attempt to applying hydrotropy technique for titrimetric estimation of ketoprofen using sodium salicylate as hydrotrope

D Tripathi, N Chaudhary, DK Sharma… - Research Journal of …, 2021 - search.proquest.com
There are various hydrotropic agents such as urea, sodium benzoate, sodium citrate,
sodium salicylate, sodium acetate, etc. that have been employed to strengthen the aqueous …

[PDF][PDF] A simple spectrophotometric estimation of Ketoprofen in tablets using mixed hydrotropy

V Nair, MS Rajput - Der Pharma Chemica, 2010 - researchgate.net
The present investigation illustrates the application of mixed hydrotropy. A novel, safe and
sensitive method of spectrophotometric estimation in the ultraviolet region has been …