Animal models for HIV/AIDS research
T Hatziioannou, DT Evans - Nature Reviews Microbiology, 2012 - nature.com
The AIDS pandemic continues to present us with unique scientific and public health
challenges. Although the development of effective antiretroviral therapy has been a major …
challenges. Although the development of effective antiretroviral therapy has been a major …
Specific memory within innate immune systems
J Kurtz - Trends in immunology, 2005 - cell.com
Research into immune defense has been considerably enriched by the increasing focus on
innate immunity. This type of immunity is still considered to lack specific memory, largely …
innate immunity. This type of immunity is still considered to lack specific memory, largely …
The preclinical pharmacology of the high affinity anti-IL-6R Nanobody® ALX-0061 supports its clinical development in rheumatoid arthritis
M Van Roy, C Ververken, E Beirnaert… - Arthritis research & …, 2015 - Springer
Introduction The pleiotropic cytokine interleukin-6 (IL-6) plays an important role in the
pathogenesis of different diseases, including rheumatoid arthritis (RA). ALX-0061 is a …
pathogenesis of different diseases, including rheumatoid arthritis (RA). ALX-0061 is a …
Mamu-B*08-Positive Macaques Control Simian Immunodeficiency Virus Replication
JT Loffredo, J Maxwell, Y Qi, CE Glidden… - Journal of …, 2007 - Am Soc Microbiol
Certain major histocompatibility complex (MHC) class I alleles are associated with the
control of human immunodeficiency virus and simian immunodeficiency virus (SIV) …
control of human immunodeficiency virus and simian immunodeficiency virus (SIV) …
Major histocompatibility complex genoty** with massively parallel pyrosequencing
RW Wiseman, JA Karl, BN Bimber, CE O'leary… - Nature medicine, 2009 - nature.com
Major histocompatibility complex (MHC) genetics dictate adaptive cellular immune
responses, making robust MHC genoty** methods essential for studies of infectious …
responses, making robust MHC genoty** methods essential for studies of infectious …
How host genetics dictates successful viral zoonosis
Viruses of wild and domestic animals can infect humans in a process called zoonosis, and
these events can give rise to explosive epidemics such as those caused by the HIV and …
these events can give rise to explosive epidemics such as those caused by the HIV and …
[HTML][HTML] Cytomegalovirus-vaccine-induced unconventional T cell priming and control of SIV replication is conserved between primate species
D Malouli, RM Gilbride, HL Wu, JM Hwang, N Maier… - Cell host & …, 2022 - cell.com
Strain 68-1 rhesus cytomegalovirus expressing simian immunodeficiency virus (SIV)
antigens (RhCMV/SIV) primes MHC-E-restricted CD8+ T cells that control SIV replication in …
antigens (RhCMV/SIV) primes MHC-E-restricted CD8+ T cells that control SIV replication in …
Methods for MHC genoty** in non‐model vertebrates
W Babik - Molecular ecology resources, 2010 - Wiley Online Library
Genes of the major histocompatibility complex (MHC) are considered a paradigm of
adaptive evolution at the molecular level and as such are frequently investigated by …
adaptive evolution at the molecular level and as such are frequently investigated by …
MHC gene copy number variation in Tasmanian devils: implications for the spread of a contagious cancer
Tasmanian devils face extinction owing to the emergence of a contagious cancer. Devil
facial tumour disease (DFTD) is a clonal cancer spread owing to a lack of major …
facial tumour disease (DFTD) is a clonal cancer spread owing to a lack of major …
Complete sequencing of a cynomolgus macaque major histocompatibility complex haplotype
Macaques provide the most widely used nonhuman primate models for studying the
immunology and pathogenesis of human diseases. Although the macaque major …
immunology and pathogenesis of human diseases. Although the macaque major …