Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems

M Shi, KJ McHugh - Advanced drug delivery reviews, 2023 - Elsevier
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …

Natural product-based nanoformulations for cancer therapy: Opportunities and challenges

D Kashyap, HS Tuli, MB Yerer, A Sharma, K Sak… - Seminars in cancer …, 2021 - Elsevier
Application of natural product-based nanoformulations for the treatment of different human
diseases, such as cancer, is an emerging field. The conventional cancer therapeutic …

Protein nanoparticles: promising platforms for drug delivery applications

A Jain, SK Singh, SK Arya, SC Kundu… - … Biomaterials Science & …, 2018 - ACS Publications
The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …

LCST polymers: Thermoresponsive nanostructured assemblies towards bioapplications

G Pasparakis, C Tsitsilianis - Polymer, 2020 - Elsevier
Thermoresponsive polymers constitute an important class of materials for biomedical
application due to their thermally reversible coil-to-globule transition which can be exploited …

Protein nanoparticles as drug delivery carriers for cancer therapy

W Lohcharoenkal, L Wang, YC Chen… - BioMed research …, 2014 - Wiley Online Library
Nanoparticles have increasingly been used for a variety of applications, most notably for the
delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery …

Polymeric conjugates for drug delivery

N Larson, H Ghandehari - Chemistry of Materials, 2012 - ACS Publications
The field of polymer therapeutics has evolved over the past decade and has resulted in the
development of polymer–drug conjugates with a wide variety of architectures and chemical …

Stimuli-responsive nanoparticles, nanogels and capsules for integrated multifunctional intelligent systems

M Motornov, Y Roiter, I Tokarev, S Minko - Progress in polymer science, 2010 - Elsevier
In this review we provide an analysis of recent literature reports on the synthesis and
applications of stimuli-responsive polymeric and hybrid nanostructured particles in a range …

[HTML][HTML] Temperature-sensitive polymers to promote heat-triggered drug release from liposomes: Towards bypassing EPR

M Amin, T Lammers, TLM Ten Hagen - Advanced Drug Delivery Reviews, 2022 - Elsevier
Heat-triggered drug release from temperature-sensitive nanocarriers upon the application of
mild hyperthermia is a promising approach to achieve site-specific delivery of drugs. The …

Lipid–Peptide Vesicle Nanoscale Hybrids for Triggered Drug Release by Mild Hyperthermia in Vitro and in Vivo

ZS Al-Ahmady, WT Al-Jamal, JV Bossche, TT Bui… - ACS …, 2012 - ACS Publications
The present study describes leucine zipper peptide–lipid hybrid nanoscale vesicles
engineered by self-assembled anchoring of the amphiphilic peptide within the lipid bilayer …

Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines

J Despanie, JP Dhandhukia, SF Hamm-Alvarez… - Journal of Controlled …, 2016 - Elsevier
Elastin-like polypeptides (ELPs) constitute a genetically engineered class of 'protein
polymers' derived from human tropoelastin. They exhibit a reversible phase separation …