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Strategies for overcoming protein and peptide instability in biodegradable drug delivery systems
The global pharmaceutical market has recently shifted its focus from small molecule drugs to
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …
peptide, protein, and nucleic acid drugs, which now comprise a majority of the top-selling …
Natural product-based nanoformulations for cancer therapy: Opportunities and challenges
Application of natural product-based nanoformulations for the treatment of different human
diseases, such as cancer, is an emerging field. The conventional cancer therapeutic …
diseases, such as cancer, is an emerging field. The conventional cancer therapeutic …
Protein nanoparticles: promising platforms for drug delivery applications
The development of drug delivery systems using nanoparticles as carriers for small and
large therapeutic molecules remains a rapidly growing area of research. The advantages of …
large therapeutic molecules remains a rapidly growing area of research. The advantages of …
LCST polymers: Thermoresponsive nanostructured assemblies towards bioapplications
Thermoresponsive polymers constitute an important class of materials for biomedical
application due to their thermally reversible coil-to-globule transition which can be exploited …
application due to their thermally reversible coil-to-globule transition which can be exploited …
Protein nanoparticles as drug delivery carriers for cancer therapy
W Lohcharoenkal, L Wang, YC Chen… - BioMed research …, 2014 - Wiley Online Library
Nanoparticles have increasingly been used for a variety of applications, most notably for the
delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery …
delivery of therapeutic and diagnostic agents. A large number of nanoparticle drug delivery …
Polymeric conjugates for drug delivery
The field of polymer therapeutics has evolved over the past decade and has resulted in the
development of polymer–drug conjugates with a wide variety of architectures and chemical …
development of polymer–drug conjugates with a wide variety of architectures and chemical …
Stimuli-responsive nanoparticles, nanogels and capsules for integrated multifunctional intelligent systems
M Motornov, Y Roiter, I Tokarev, S Minko - Progress in polymer science, 2010 - Elsevier
In this review we provide an analysis of recent literature reports on the synthesis and
applications of stimuli-responsive polymeric and hybrid nanostructured particles in a range …
applications of stimuli-responsive polymeric and hybrid nanostructured particles in a range …
[HTML][HTML] Temperature-sensitive polymers to promote heat-triggered drug release from liposomes: Towards bypassing EPR
Heat-triggered drug release from temperature-sensitive nanocarriers upon the application of
mild hyperthermia is a promising approach to achieve site-specific delivery of drugs. The …
mild hyperthermia is a promising approach to achieve site-specific delivery of drugs. The …
Lipid–Peptide Vesicle Nanoscale Hybrids for Triggered Drug Release by Mild Hyperthermia in Vitro and in Vivo
The present study describes leucine zipper peptide–lipid hybrid nanoscale vesicles
engineered by self-assembled anchoring of the amphiphilic peptide within the lipid bilayer …
engineered by self-assembled anchoring of the amphiphilic peptide within the lipid bilayer …
Elastin-like polypeptides: Therapeutic applications for an emerging class of nanomedicines
Elastin-like polypeptides (ELPs) constitute a genetically engineered class of 'protein
polymers' derived from human tropoelastin. They exhibit a reversible phase separation …
polymers' derived from human tropoelastin. They exhibit a reversible phase separation …