Magnetic nanoparticles in MR imaging and drug delivery

C Sun, JSH Lee, M Zhang - Advanced drug delivery reviews, 2008 - Elsevier
Magnetic nanoparticles (MNPs) possess unique magnetic properties and the ability to
function at the cellular and molecular level of biological interactions making them an …

Recent advances in iron oxide nanocrystal technology for medical imaging

C Corot, P Robert, JM Idée, M Port - Advanced drug delivery reviews, 2006 - Elsevier
Superparamagnetic iron oxide particles (SPIO and USPIO) have a variety of applications in
molecular and cellular imaging. Most of the recent research has concerned cellular imaging …

Superparamagnetic iron oxide based MRI contrast agents: Current status of clinical application

YXJ Wang - Quantitative imaging in medicine and surgery, 2011 - pmc.ncbi.nlm.nih.gov
Superparamagnetic iron oxide (SPIO) MR contrast agents are composed of nano-sized iron
oxide crystals coated with dextran or carboxydextran. Two SPIO agents are clinically …

Multifunctional magnetic nanoparticles for targeted imaging and therapy

JR McCarthy, R Weissleder - Advanced drug delivery reviews, 2008 - Elsevier
Magnetic nanoparticles have become important tools for the imaging of prevalent diseases,
such as cancer, atherosclerosis, diabetes, and others. While first generation nanoparticles …

Inflammation and atherosclerosis: novel insights into plaque formation and destabilization

G Stoll, M Bendszus - Stroke, 2006 - ahajournals.org
Background and Purpose—The simplistic view of atherosclerosis as a disorder of
pathological lipid deposition has been redefined by the more complex concept of an …

From vulnerable plaque to vulnerable patient—part III: executive summary of the Screening for Heart Attack Prevention and Education (SHAPE) Task Force report

M Naghavi, E Falk, HS Hecht, MJ Jamieson… - The American journal of …, 2006 - Elsevier
Screening for early-stage asymptomatic cancers (eg, cancers of breast and colon) to prevent
late-stage malignancies has been widely accepted. However, although atherosclerotic …

Noninvasive detection of macrophages using a nanoparticulate contrast agent for computed tomography

F Hyafil, JC Cornily, JE Feig, R Gordon, E Vucic… - Nature medicine, 2007 - nature.com
Sudden fibrous cap disruption of'high-risk'atherosclerotic plaques can trigger the formation
of an occlusive thrombus in coronary arteries, causing acute coronary syndromes. High-risk …

Inflammatory changes in the aneurysm wall: a review

R Tulamo, J Frösen, J Hernesniemi… - Journal of …, 2018 - jnis.bmj.com
Rupture of a saccular intracranial artery aneurysm (IA) causes subarachnoid hemorrhage, a
significant cause of stroke and death. The current treatment options, endovascular coiling …

The ATHEROMA (Atorvastatin Therapy: Effects on Reduction of Macrophage Activity) Study: evaluation using ultrasmall superparamagnetic iron oxide-enhanced …

TY Tang, SPS Howarth, SR Miller, MJ Graves… - Journal of the American …, 2009 - jacc.org
Objectives: The aim of this study was to evaluate the effects of low-dose (10 mg) and high-
dose (80 mg) atorvastatin on carotid plaque inflammation as determined by ultrasmall …