Hydrogels for RNA delivery

R Zhong, S Talebian, BB Mendes, G Wallace… - Nature materials, 2023 - nature.com
RNA-based therapeutics have shown tremendous promise in disease intervention at the
genetic level, and some have been approved for clinical use, including the recent COVID-19 …

Advanced drug delivery systems and artificial skin grafts for skin wound healing

HS Kim, X Sun, JH Lee, HW Kim, X Fu… - Advanced drug delivery …, 2019 - Elsevier
Cutaneous injuries, especially chronic wounds, burns, and skin wound infection, require
painstakingly long-term treatment with an immense financial burden to healthcare systems …

Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment

G Huang, F Li, X Zhao, Y Ma, Y Li, M Lin, G **… - Chemical …, 2017 - ACS Publications
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Degradability and clearance of silicon, organosilica, silsesquioxane, silica mixed oxide, and mesoporous silica nanoparticles

JG Croissant, Y Fatieiev, NM Khashab - Advanced materials, 2017 - Wiley Online Library
The biorelated degradability and clearance of siliceous nanomaterials have been
questioned worldwide, since they are crucial prerequisites for the successful translation in …

Advanced therapeutic dressings for effective wound healing—a review

J Boateng, O Catanzano - Journal of pharmaceutical sciences, 2015 - Elsevier
Advanced therapeutic dressings that take active part in wound healing to achieve rapid and
complete healing of chronic wounds is of current research interest. There is a desire for …

Acellular and cellular approaches to improve diabetic wound healing

H Cho, MR Blatchley, EJ Duh, S Gerecht - Advanced drug delivery reviews, 2019 - Elsevier
Chronic diabetic wounds represent a huge socioeconomic burden for both affected
individuals and the entire healthcare system. Although the number of available treatment …

Gene therapy to enhance angiogenesis in chronic wounds

E Shaabani, M Sharifiaghdam, R Faridi-Majidi… - … Therapy-Nucleic Acids, 2022 - cell.com
Skin injuries and chronic non-healing wounds are one of the major global burdens on the
healthcare systems worldwide due to their difficult-to-treat nature, associated co-morbidities …

Reactive oxygen species–degradable polythioketal urethane foam dressings to promote porcine skin wound repair

P Patil, KA Russo, JT McCune, AC Pollins… - Science translational …, 2022 - science.org
Porous, resorbable biomaterials can serve as temporary scaffolds that support cell
infiltration, tissue formation, and remodeling of nonhealing skin wounds. Synthetic …

Terminally modified RNA

T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49447811&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Harnessing nucleic acids nanotechnology for bone/cartilage regeneration

Y Han, L Cao, G Li, F Zhou, L Bai, J Su - Small, 2023 - Wiley Online Library
The effective regeneration of weight‐bearing bone defects and critical‐sized cartilage
defects remains a significant clinical challenge. Traditional treatments such as autologous …