1. INTRODUCTION Indoline-2, 3-dione or indole-1H-2, 3-dione (Figure 1), commonly known
as isatin, is a well-known natural product found in plants of genus Isatis and in Couropita …

Multicomponent reactions have become increasingly popular as tools for the rapid
generation of small‐molecule libraries. However, to ensure sufficient molecular diversity and …

Piperidines are among the most important synthetic fragments for designing drugs and play
a significant role in the pharmaceutical industry. Their derivatives are present in more than …

Water is the solvent used by nature for biological chemistry. Considering the enormous
variety of biological organic synthetic pathways and the complicated molecular structures …

Optically pure nitrogenous compounds, and especially nitrogen-containing heterocycles,
have drawn intense research attention because of their frequent isolation as natural …

Multicomponent reactions are one of the most interesting concepts in modern synthetic
chemistry and, as shown in this critical review, they provide an attractive entry into pyrrole …

Simple and green synthetic procedures constitute an important goal in organic synthesis.
The combination of multicomponent reactions (MCRs) and unconventional solvents has …

Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the
synthesis of versatile heterocycles, particularly those containing structural diversity and …

Polyheterocycles are one of the most desired synthetic targets due to their numerous and
valuable applications in various fields. Multicomponent reactions (MCRs) are highly …

Owing to hindered diffusions, the application of porous catalytic materials has been limited
to relatively simple organic transformations with small substrates. Herein we report a …