Recent advances in bovine in vitro embryo production: reproductive biotechnology history and methods

LB Ferré, ME Kjelland, LB Strøbech, P Hyttel… - Animal, 2020 - cambridge.org
In vitro production (IVP) of embryos and associated technologies in cattle have shown
significant progress in recent years, in part driven by a better understanding of the full …

Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility

G Fiorentino, D Cimadomo, F Innocenti… - Human reproduction …, 2023 - academic.oup.com
BACKGROUND Folliculogenesis occurs in the highly dynamic environment of the ovary.
Follicle cyclic recruitment, neo-angiogenesis, spatial displacement, follicle atresia and …

Influence of follicular fluid and cumulus cells on oocyte quality: clinical implications

MG Da Broi, VSI Giorgi, F Wang, DL Keefe… - Journal of assisted …, 2018 - Springer
An equilibrium needs to be established by the cellular and acellular components of the
ovarian follicle if developmental competence is to be acquired by the oocyte. Both cumulus …

Signaling mechanisms and their regulation during in vivo or in vitro maturation of mammalian oocytes

P Strączyńska, K Papis, E Morawiec… - Reproductive Biology …, 2022 - Springer
In vitro fertilization (IVF) is currently one of the most effective methods of infertility treatment.
An alternative to commonly used ovarian hyperstimulation can become extracorporeal …

Age-associated changes in cumulus cells and follicular fluid: the local oocyte microenvironment as a determinant of gamete quality

E Babayev, FE Duncan - Biology of reproduction, 2022 - academic.oup.com
The ovary is the first organ to age in humans with functional decline evident already in
women in their early 30s. Reproductive aging is characterized by a decrease in oocyte …

Identification of microRNAs in human follicular fluid: characterization of microRNAs that govern steroidogenesis in vitro and are associated with polycystic ovary …

Q Sang, Z Yao, H Wang, R Feng… - The Journal of …, 2013 - academic.oup.com
Context: Human follicular fluid is a combination of proteins, metabolites, and ionic
compounds that is indicative of the general state of follicular metabolism and is associated …

Cell-secreted vesicles in equine ovarian follicular fluid contain miRNAs and proteins: a possible new form of cell communication within the ovarian follicle

JC da Silveira, DNR Veeramachaneni… - Biology of …, 2012 - academic.oup.com
Proper cell communication within the ovarian follicle is critical for the growth and maturation
of a healthy oocyte that can be fertilized and develop into an embryo. Cell communication …

Rejuvenation of aged oocyte through exposure to young follicular microenvironment

HY Wang, Z Huang, X Shen, Y Lee, XJ Song, C Shu… - Nature Aging, 2024 - nature.com
Reproductive aging is a major cause of fertility decline, attributed to decreased oocyte
quantity and developmental potential. A possible cause is aging of the surrounding follicular …

[HTML][HTML] Molecular characterization of exosomes and their microRNA cargo in human follicular fluid: bioinformatic analysis reveals that exosomal microRNAs control …

M Santonocito, M Vento, MR Guglielmino, R Battaglia… - Fertility and sterility, 2014 - Elsevier
Objective To characterize well-represented microRNAs in human follicular fluid (FF) and to
ascertain whether they are cargo of FF exosomes and whether they are involved in the …

Transcriptome profiling of granulosa cells of bovine ovarian follicles during growth from small to large antral sizes

N Hatzirodos, HF Irving-Rodgers, K Hummitzsch… - BMC genomics, 2014 - Springer
Background At later stages of folliculogenesis, the mammalian ovarian follicle contains
layers of epithelial granulosa cells surrounding an antral cavity. During follicle development …