Protective and damaging effects of stress mediators

BS McEwen - New England journal of medicine, 1998 - Mass Medical Soc
Over 60 years ago, Selye1 recognized the paradox that the physiologic systems activated by
stress can not only protect and restore but also damage the body. What links these …

Stress, adaptation, and disease: Allostasis and allostatic load

BS McEwen - Annals of the New York academy of sciences, 1998 - Wiley Online Library
Adaptation in the face of potentially stressful challenges involves activation of neural,
neuroendocrine and neuroendocrine‐immune mechanisms. This has been called …

[BOOK][B] The emotional brain: The mysterious underpinnings of emotional life

JE LeDoux - 1998 - books.google.com
What happens in our brains to make us feel fear, love, hate, anger, joy? do we control our
emotions, or do they control us? Do animals have emotions? How can traumatic …

Physiology and neurobiology of stress and adaptation: central role of the brain

BS McEwen - Physiological reviews, 2007 - journals.physiology.org
The brain is the key organ of the response to stress because it determines what is
threatening and, therefore, potentially stressful, as well as the physiological and behavioral …

Socioeconomic status and health: the challenge of the gradient.

NE Adler, T Boyce, MA Chesney, S Cohen… - American …, 1994 - psycnet.apa.org
SES is consistently associated with health outcomes, yet little is known about the
psychosocial and behavioral mechanisms that might explain this association. Researchers …

[BOOK][B] What babies know: Core Knowledge and Composition volume 1

E Spelke - 2022 - books.google.com
What do infants know? How does the knowledge that they begin with prepare them for
learning about the particular physical, cultural, and social world in which they live? Answers …

Central role of the brain in stress and adaptation: links to socioeconomic status, health, and disease

BS McEwen, PJ Gianaros - Annals of the New York Academy of …, 2010 - Wiley Online Library
The brain is the key organ of stress reactivity, co**, and recovery processes. Within the
brain, a distributed neural circuitry determines what is threatening and thus stressful to the …

Hippocampal place-cell sequences depict future paths to remembered goals

BE Pfeiffer, DJ Foster - Nature, 2013 - nature.com
Effective navigation requires planning extended routes to remembered goal locations.
Hippocampal place cells have been proposed to have a role in navigational planning, but …

The neurobiology of stress: from serendipity to clinical relevance

BS McEwen - Brain research, 2000 - Elsevier
The hormones and other physiological agents that mediate the effects of stress on the body
have protective and adaptive effects in the short run and yet can accelerate pathophysiology …

Stress and hippocampal plasticity

BS McEwen - Annual review of neuroscience, 1999 - annualreviews.org
▪ Abstract The hippocampus is a target of stress hormones, and it is an especially plastic and
vulnerable region of the brain. It also responds to gonadal, thyroid, and adrenal hormones …