Small-molecule fluorescence-based probes for interrogating major organ diseases

HH Han, H Tian, Y Zang, AC Sedgwick, J Li… - Chemical Society …, 2021 - pubs.rsc.org
Chemical tools that allow the real-time monitoring of organ function and the visualisation of
organ-related processes at the cellular level are of great importance in biological research …

Autoimmune gastritis

MV Lenti, M Rugge, E Lahner, E Miceli… - Nature Reviews …, 2020 - nature.com
Autoimmune gastritis (AIG) is an increasingly prevalent, organ-specific, immune-mediated
disorder characterized by the destruction of gastric parietal cells, leading to the loss of …

The oral–gut microbiome axis in health and disease

BJ Kunath, C De Rudder, CC Laczny… - Nature Reviews …, 2024 - nature.com
The human body hosts trillions of microorganisms throughout many diverse habitats with
different physico-chemical characteristics. Among them, the oral cavity and the gut harbour …

[HTML][HTML] Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution

GA Busslinger, BLA Weusten, A Bogte, H Begthel… - Cell Reports, 2021 - cell.com
The upper gastrointestinal tract, consisting of the esophagus, stomach, and duodenum,
controls food transport, digestion, nutrient uptake, and hormone production. By single-cell …

Oral drug delivery platforms for biomedical applications

J Ouyang, Z Zhang, B Deng, J Liu, L Wang, H Liu… - Materials Today, 2023 - Elsevier
Oral administration is perhaps the most commonly used and acceptable route for drug
delivery to patients, mainly due to its non-invasiveness, simplicity, and versatility …

Mass eradication of Helicobacter pylori to reduce gastric cancer incidence and mortality: a long-term cohort study on Matsu Islands

TH Chiang, WJ Chang, SLS Chen, AMF Yen, JCY Fann… - Gut, 2021 - gut.bmj.com
Objective Although mass eradication of Helicobacter pylori has been proposed as a means
to eliminate gastric cancer, its long-term effects remain unclear. Design Mass eradication of …

Management of Helicobacter pylori infection—the Maastricht V/Florence consensus report

P Malfertheiner, F Mégraud, CA O'Morain, JP Gisbert… - Gut, 2017 - gut.bmj.com
Important progress has been made in the management of Helicobacter pylori infection and
in this fifth edition of the Maastricht Consensus Report, key aspects related to the clinical role …

Microbial ecology along the gastrointestinal tract

ET Hillman, H Lu, T Yao, CH Nakatsu - Microbes and environments, 2017 - jstage.jst.go.jp
The ecosystem of the human gastrointestinal (GI) tract traverses a number of environmental,
chemical, and physical conditions because it runs from the oral cavity to the anus. These …

[HTML][HTML] Association between Helicobacter pylori eradication and gastric cancer incidence: a systematic review and meta-analysis

YC Lee, TH Chiang, CK Chou, YK Tu, WC Liao, MS Wu… - Gastroenterology, 2016 - Elsevier
Background & Aims Eradication of Helicobacter pylori infection has been reported to reduce
the risk of gastric cancer among asymptomatic individuals in high-risk areas. The magnitude …

Human gastric cancer modelling using organoids

T Seidlitz, SR Merker, A Rothe, F Zakrzewski… - Gut, 2019 - gut.bmj.com
Objective Gastric cancer is the second leading cause of cancer-related deaths and the fifth
most common malignancy worldwide. In this study, human and mouse gastric cancer …