Sarcopenia and frailty in decompensated cirrhosis

P Tandon, AJ Montano-Loza, JC Lai, S Dasarathy… - Journal of …, 2021 - Elsevier
In patients with decompensated cirrhosis, sarcopenia and frailty are prevalent. Although
several definitions exist for these terms, in the field of hepatology, sarcopenia has commonly …

Personalised management of patients with hepatocellular carcinoma: a multiparametric therapeutic hierarchy concept

A Vitale, G Cabibbo, M Iavarone, L Viganò… - The Lancet …, 2023 - thelancet.com
Advances in the surgical and systemic therapeutic landscape of hepatocellular carcinoma
have increased the complexity of patient management. A dynamic adaptation of the …

[HTML][HTML] Report from the American Society of Transplantation on frailty in solid organ transplantation

J Kobashigawa, D Dadhania, S Bhorade… - American Journal of …, 2019 - Elsevier
A consensus conference on frailty in kidney, liver, heart, and lung transplantation sponsored
by the American Society of Transplantation (AST) and endorsed by the American Society of …

Frailty associated with waitlist mortality independent of ascites and hepatic encephalopathy in a multicenter study

JC Lai, RS Rahimi, EC Verna, MR Kappus, MA Dunn… - Gastroenterology, 2019 - Elsevier
Background & Aims Frailty is associated with mortality in patients with cirrhosis. We
measured frailty using 3 simple tests and calculated Liver Frailty Index (LFI) scores for …

Exercise in cirrhosis: translating evidence and experience to practice

P Tandon, KP Ismond, K Riess, A Duarte-Rojo… - Journal of …, 2018 - Elsevier
Physical inactivity, sarcopenia, and frailty are highly prevalent, independent predictors of
morbidity and mortality in patients with cirrhosis. Across a range of chronic diseases …

Merits and boundaries of the BCLC staging and treatment algorithm: Learning from the past to improve the future with a novel proposal

F Trevisani, A Vitale, M Kudo, L Kulik, JW Park… - Journal of …, 2024 - Elsevier
Summary In this Expert Opinion, we thoroughly analyse the Barcelona Clinic Liver Cancer
(BCLC) staging and treatment algorithm for hepatocellular carcinoma (HCC) that, since …

[HTML][HTML] Frailty in liver transplantation: an expert opinion statement from the American Society of Transplantation Liver and Intestinal Community of Practice

JC Lai, CJ Sonnenday, EB Tapper… - American journal of …, 2019 - Elsevier
Frailty has emerged as a powerful predictor of outcomes in patients with cirrhosis and has
inevitably made its way into decision making within liver transplantation. In an effort to …

Measuring frailty in younger populations: a rapid review of evidence

GF Spiers, TP Kunonga, A Hall, F Beyer, E Boulton… - BMJ open, 2021 - bmjopen.bmj.com
Objectives Frailty is typically assessed in older populations. Identifying frailty in adults aged
under 60 years may also have value, if it supports the delivery of timely care. We sought to …

[PDF][PDF] Physical function, physical activity, and quality of life after liver transplantation

MA Dunn, SS Rogal, A Duarte‐Rojo… - Liver …, 2020 - Wiley Online Library
Robust physical activity after liver transplantation is an important determinant of longterm
health, similar in its importance to the value of pretransplant activity for withstanding the …

Frailty in advanced liver disease

R Laube, H Wang, L Park, JK Heyman… - Liver …, 2018 - Wiley Online Library
Prognostication of patients with cirrhosis is complex, depending on more than just the
severity of liver disease. Scores such as the model for end‐stage liver disease (MELD) and …