Drug resistance in cancers: A free pass for bullying

J Li, X Li, Q Guo - Cells, 2022 - mdpi.com
The cancer burden continues to grow globally, and drug resistance remains a substantial
challenge in cancer therapy. It is well established that cancerous cells with clonal dysplasia …

Analysis of N‐ and O‐linked site‐specific glycosylation by ion mobility mass spectrometry: State of the art and future directions

M Girgis, G Petruncio, P Russo, S Peyton, M Paige… - …, 2024 - Wiley Online Library
Glycosylation, the major post‐translational modification of proteins, significantly increases
the diversity of proteoforms. Glycans are involved in a variety of pivotal structural and …

[HTML][HTML] Integrin-based prognostic model predicts survival, immunotherapy response, and drug sensitivity in gastric cancer

Y Hu, Y Chen, M Wu, C Qian, J Chen, K Wang… - Biomedical …, 2024 - Elsevier
Background Extracellular matrix (ECM) acts as a physical barrier to tumors, resulting in the
lysis or delay of drug delivery. Integrins (ITGs) are essential for tumor cell-ECM interactions …

[HTML][HTML] Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review

M Aidiel, M Abdul Mutalib, R Ramasamy, NN Nik Ramli… - Molecules, 2025 - mdpi.com
2-phenylchromen-4-one, commonly known as flavone, plays multifaceted roles in biological
response that can be abundantly present in natural sources. The methoxy group in naturally …

Two-Dimensional-PAGE Coupled with nLC-MS/MS-Based Identification of Differentially Expressed Proteins and Tumorigenic Pathways in MCF7 Breast Cancer Cells …

M Jayathirtha, T Jayaweera, D Whitham, I Sullivan… - Molecules, 2023 - mdpi.com
The identification of new cancer-associated genes/proteins, the characterization of their
expression variation, the interactomics-based assessment of differentially expressed …

Comprehensive review and updated analysis of DNA methylation in hepatocellular carcinoma: From basic research to clinical application

L Su, J Bu, J Yu, M **, G Meng… - Clinical and Translational …, 2024 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a primary malignant tumour, ranking second in global
mortality rates and posing significant health threats. Epigenetic alterations, particularly DNA …

A hybrid computational model of cancer spheroid growth with ribose-induced collagen stiffening

M Botticelli, J Metzcar, T Phillips, S Cox… - bioRxiv, 2024 - biorxiv.org
Metastasis, the leading cause of death in cancer patients, arises when cancer cells
disseminate from a primary solid tumour to distant organs. Growth and invasion of the solid …

Desarrollo y evaluación de un nanosistema para la detección de células que sobreexpresan HER2

PY Carrión García - 2023 - eprints.uanl.mx
Área de Estudio: Nanomedicina Propósito y Método del Estudio: El receptor 2 del factor de
crecimiento epidérmico humano (HER2) es una proteína transmembranal involucrada en el …

Integrin beta 1 and fibronectin mediate extracellular vesicle uptake and functional RNA delivery

OM Elsharkasy, WS de Voogt, ML Tognoli… - Journal of Biological … - jbc.org
Extracellular vesicles (EVs) are cell-derived vesicles secreted by all cell types into the
extracellular spaces. EVs comprise a heterogenous population of vesicles that carry …

[PDF][PDF] Novel Mechanistic Insights into the Anticancer Potential of Methoxyflavones Analogs: A Review

M Aidiel, MA Mutalib, R Ramasamy, NNN Ramli… - 2024 - preprints.org
2-phenylchromen-4-one, commonly known as flavone, plays multifaceted roles in biological
response, largely due to its abundance in natural sources. The methoxy group in naturally …