The gut–brain axis and its relation to Parkinson's disease: a review

EM Klann, U Dissanayake, A Gurrala… - Frontiers in aging …, 2022 - frontiersin.org
Parkinson's disease is a chronic neurodegenerative disease characterized by the
accumulation of misfolded alpha-synuclein protein (Lewy bodies) in dopaminergic neurons …

Multi-modal deep learning diagnosis of Parkinson's disease—a systematic review

V Skaramagkas, A Pentari… - … on Neural Systems …, 2023 - ieeexplore.ieee.org
Parkinson's Disease (PD) is among the most frequent neurological disorders. Approaches
that employ artificial intelligence and notably deep learning, have been extensively …

Integrating multimodal and multiscale connectivity blueprints of the human cerebral cortex in health and disease

JY Hansen, G Shafiei, K Voigt, EX Liang, SML Cox… - PLoS …, 2023 - journals.plos.org
The brain is composed of disparate neural populations that communicate and interact with
one another. Although fiber bundles, similarities in molecular architecture, and synchronized …

Targeting Nrf2 signaling pathway and oxidative stress by resveratrol for Parkinson's disease: an overview and update on new developments

MY Zamanian, RMR Parra, A Soltani… - Molecular Biology …, 2023 - Springer
Parkinson's disease (PD) as a prevalent neurodegenerative condition impairs motor function
and is caused by the progressive deterioration of nigrostriatal dopaminergic (DAergic) …

Resveratrol attenuates rotenone-induced inflammation and oxidative stress via STAT1 and Nrf2/Keap1/SLC7A11 pathway in a microglia cell line

W Sun, H Li, Y Shen, H **ao - Pathology-Research and Practice, 2021 - Elsevier
Scope Resveratrol is abundant in grapes. A protective role for resveratrol in anti-oxidation
and anti-inflammatory has been demonstrated. Rotenone is a pesticide, used to make …

Machine learning within the Parkinson's progression markers initiative: Review of the current state of affairs

RT Gerraty, A Provost, L Li, E Wagner… - Frontiers in Aging …, 2023 - frontiersin.org
The Parkinson's Progression Markers Initiative (PPMI) has collected more than a decade's
worth of longitudinal and multi-modal data from patients, healthy controls, and at-risk …

Identification of Parkinson's disease subtypes from resting‐state electroencephalography

S Yassine, U Gschwandtner, M Auffret… - Movement …, 2023 - Wiley Online Library
Background Parkinson's disease (PD) patients present with a heterogeneous clinical
phenotype, including motor, cognitive, sleep, and affective disruptions. However, this …

Effect of probiotic supplementation on gastrointestinal motility, inflammation, motor, non-motor symptoms and mental health in Parkinson's disease: a meta-analysis of …

JM Park, SC Lee, C Ham, YW Kim - Gut Pathogens, 2023 - Springer
Background Parkinson's disease (PD) is the second most common neurodegenerative
disease worldwide. Gut dysbiosis is hypothesized to cause PD; therefore, whether probiotics …

[HTML][HTML] Genetic-based patient stratification in Alzheimer's disease

L Hernández-Lorenzo, F García-Gutiérrez… - Scientific Reports, 2024 - nature.com
Alzheimer's disease (AD) shows a high pathological and symptomatological heterogeneity.
To study this heterogeneity, we have developed a patient stratification technique based on …

Combining neuroimaging and omics datasets for disease classification using graph neural networks

YH Chan, C Wang, WK Soh… - Frontiers in Neuroscience, 2022 - frontiersin.org
Both neuroimaging and genomics datasets are often gathered for the detection of
neurodegenerative diseases. Huge dimensionalities of neuroimaging data as well as omics …