Dearomatisation reactions of (hetero) arenes have been widely employed as efficient
methods to obtain highly substituted saturated cyclic compounds for over a century. In recent …

The range of application of organic compounds is enormous due to that organic compounds
are structurally diverse. They either form the basis of or are important constituents of many …

The sustainable production of value-added N-heterocycles from available biomass allows to
reduce the reliance on fossil resources and creates possibilities for economically and …

Multicomponent reactions (MCRs) receive increasing attention because they address both
diversity and complexity in organic synthesis. Thus, in principle diverse sets of relatively …

Optically pure nitrogenous compounds, and especially nitrogen-containing heterocycles,
have drawn intense research attention because of their frequent isolation as natural …

Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

Nucleophilic phosphine catalysis is a practical and powerful tool for the synthesis of various
heterocyclic compounds with the advantages of environmentally friendly, metal-free, and …

Piperidine is an important pharmacophore, a privileged scaffold and an excellent
heterocyclic system in the field of drug discovery which provides numerous opportunities in …

Although tertiary phosphines have emerged as remarkably versatile nucleophilic catalysts,
there has been only very limited progress in achieving asymmetric catalysis with chiral …

Metal-catalyzed olefin metathesis has become one of the most widely used organometallic
transformations for carbon-carbon formation in organic synthesis. For this reason, the Royal …