Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic disease of the lung that is marked by
progressive decline in pulmonary function and ultimately respiratory failure. Genetic and …

Cells interact with their surrounding environment through a combination of static and
dynamic mechanical signals that vary over stimulus types, intensity, space, and time …

The lung's unique extracellular matrix (ECM), while providing structural support for cells, is
critical in the regulation of developmental organogenesis, homeostasis and injury-repair …

Epithelial-Mesenchymal Transition (EMT) is a critical process in embryonic development in
which epithelial cells undergo a transdifferentiation into mesenchymal cells. This process is …

Pulmonary fibrosis is characterised by excessive scarring in the lung which leads to
compromised lung function, serious breathing problems and in some diseases, death. It …

The percutaneous device dilemma describes etiological factors, centered around the
disrupted epithelial tissue surrounding non-remodelable devices, that contribute to rampant …

The extracellular matrix (ECM) provides structural support and imparts a wide variety of
environmental cues to cells. In the past decade, a growing body of work revealed that the …

Many pathologic conditions lead to the development of tissue scarring and fibrosis, which
are characterized by the accumulation of abnormal extracellular matrix (ECM) and changes …

Lung fibrosis, one of the major post‐COVID complications, is a progressive and ultimately
fatal disease without a cure. Here, an organ‐and disease‐specific in vitro mini‐lung fibrosis …

Inflammatory bowel disease (IBD) continues to increase in prevalence in industrialized
countries. Major complications of IBD include formation of fibrotic strictures, fistulas, reduced …