Dyslipidaemia has a prominent role in the onset of notorious atherosclerosis, a disease of
medium to large arteries. Atherosclerosis is the prime root of cardiovascular events …

Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary
heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and …

The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

Objective The development of these guidelines is mandated by the American Association of
Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology …

PART I THE ENDOTHELIUM has long been viewed as an inert cellophane-like membrane
that lines the circulatory system with its primary essential function being the maintenance of …

Cardiovascular disease is a major complication of diabetes mellitus, and improved
strategies for prevention and treatment are needed. Endothelial dysfunction contributes to …

Defining new approaches for the prevention and treatment of atherosclerosis is an important
priority. Recently, measurement of endothelial function in patients has emerged as a useful …

Objectives. This study assessed whether aging is associated with progressive endothelial
dysfunction, whether the pattern of any age-related decline in vascular health is different in …

Endothelial dysfunction is a well established response to cardiovascular risk factors and
precedes the development of atherosclerosis. Endothelial dysfunction is involved in lesion …

AACE= American Association of Clinical Endocrinologists; ATP= Adult Treatment Panel;
apo= apolipoprotein; BEL= best evidence level; CAD= coronary artery disease; CPG …