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Cysteine oxidations in mitochondrial membrane proteins: the case of VDAC isoforms in mammals
Cysteine residues are reactive amino acids that can undergo several modifications driven by
redox reagents. Mitochondria are the source of an abundant production of radical species …
redox reagents. Mitochondria are the source of an abundant production of radical species …
MCU-induced mitochondrial calcium uptake promotes mitochondrial biogenesis and colorectal cancer growth
Y Liu, M **, Y Wang, J Zhu, R Tan, J Zhao… - Signal transduction and …, 2020 - nature.com
Mitochondrial calcium uniporter (MCU) has an important role in regulating mitochondrial
calcium (Ca2+) homeostasis. Dysregulation of mitochondrial Ca2+ homeostasis has been …
calcium (Ca2+) homeostasis. Dysregulation of mitochondrial Ca2+ homeostasis has been …
Integration of superoxide formation and cristae morphology for mitochondrial redox signaling
L Plecitá-Hlavatá, P Ježek - The International Journal of Biochemistry & …, 2016 - Elsevier
The mitochondrial network provides the central cell's energetic and regulatory unit, which
besides ATP and metabolite production participates in cellular signaling through regulated …
besides ATP and metabolite production participates in cellular signaling through regulated …
[HTML][HTML] The mitochondrial calcium uniporter (MCU) activates mitochondrial respiration and enhances mobility by regulating mitochondrial redox state
Regulation of mitochondrial redox balance is emerging as a key event for cell signaling in
both physiological and pathological conditions. However, the link between the mitochondrial …
both physiological and pathological conditions. However, the link between the mitochondrial …
[HTML][HTML] Mechanisms of retinal damage after ocular alkali burns
Alkali burns to the eye constitute a leading cause of worldwide blindness. In recent case
series, corneal transplantation revealed unexpected damage to the retina and optic nerve in …
series, corneal transplantation revealed unexpected damage to the retina and optic nerve in …
The plant product quinic acid activates Ca2+‐dependent mitochondrial function and promotes insulin secretion from pancreatic beta cells
E Heikkilä, A Hermant, J Thevenet… - British journal of …, 2019 - Wiley Online Library
Background and Purpose Quinic acid (QA) is an abundant natural compound from plant
sources which may improve metabolic health. However, little attention has been paid to its …
sources which may improve metabolic health. However, little attention has been paid to its …
Targeting mitochondrial calcium uptake with the natural flavonol kaempferol, to promote metabolism/secretion coupling in pancreatic β-cells
Pancreatic β-cells secrete insulin to lower blood glucose, following a meal. Maintenance of β-
cell function is essential to preventing type 2 diabetes. In pancreatic β-cells, mitochondrial …
cell function is essential to preventing type 2 diabetes. In pancreatic β-cells, mitochondrial …
[HTML][HTML] Mitochondria-mediated damage to dopaminergic neurons in Parkinson's disease
XL Liu, YD Wang, XM Yu, DW Li… - … Journal of Molecular …, 2018 - spandidos-publications.com
Mitochondria are important organelles in virtually all eukaryotic cells, and are involved in a
wide range of physiological and pathophysiological processes. Besides the generation of …
wide range of physiological and pathophysiological processes. Besides the generation of …
Sodium lauryl sulfate stimulates the generation of reactive oxygen species through interactions with cell membranes
T Mizutani, R Mori, M Hirayama, Y Sagawa… - Journal of oleo …, 2016 - jstage.jst.go.jp
Sodium lauryl sulfate (SLS), a representative anionic surfactant, is well-known to induce
rough skin following single or multiple topical applications. The mechanism by which SLS …
rough skin following single or multiple topical applications. The mechanism by which SLS …
[HTML][HTML] Overexpression of hexokinase 2 reduces mitochondrial calcium overload in coronary endothelial cells of type 2 diabetic mice
M Pan, Y Han, A Basu, A Dai, R Si… - … of Physiology-Cell …, 2018 - journals.physiology.org
Coronary microvascular rarefaction, due to endothelial cell (EC) dysfunction, is one of the
causes of increased morbidity and mortality in diabetes. Coronary ECs in diabetes are more …
causes of increased morbidity and mortality in diabetes. Coronary ECs in diabetes are more …