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Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …
exercise training are a potent stimulus for physiological adaptation in many organs …
Skeletal muscle: A review of molecular structure and function, in health and disease
Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …
the structural and functional complexity of this important anatomical tissue, designed to …
Diversity and versatility of p38 kinase signalling in health and disease
B Canovas, AR Nebreda - Nature reviews Molecular cell biology, 2021 - nature.com
The ability of cells to deal with different types of stressful situations in a precise and
coordinated manner is key for survival and involves various signalling networks. Over the …
coordinated manner is key for survival and involves various signalling networks. Over the …
A muscle stem cell support group: coordinated cellular responses in muscle regeneration
Skeletal muscle has an extraordinary regenerative capacity due to the activity of tissue-
specific muscle stem cells. Consequently, these cells have received the most attention in …
specific muscle stem cells. Consequently, these cells have received the most attention in …
[HTML][HTML] Stem cell aging in skeletal muscle regeneration and disease
Skeletal muscle comprises 30–40% of the weight of a healthy human body and is required
for voluntary movements in humans. Mature skeletal muscle is formed by multinuclear cells …
for voluntary movements in humans. Mature skeletal muscle is formed by multinuclear cells …
Function and inhibition of P38 MAP kinase signaling: Targeting multiple inflammation diseases
J Wang, Y Liu, Y Guo, C Liu, Y Yang, X Fan… - Biochemical …, 2024 - Elsevier
Inflammation is a natural host defense mechanism that protects the body from pathogenic
microorganisms. A growing body of research suggests that inflammation is a key factor in …
microorganisms. A growing body of research suggests that inflammation is a key factor in …
The role of the kynurenine pathway in the pathophysiology of frailty, sarcopenia, and osteoporosis
J Ballesteros, D Rivas, G Duque - Nutrients, 2023 - mdpi.com
Tryptophan is an essential nutrient required to generate vitamin B3 (niacin), which is mainly
involved in energy metabolism and DNA production. Alterations in tryptophan metabolism …
involved in energy metabolism and DNA production. Alterations in tryptophan metabolism …
Bioprocessing technology of muscle stem cells: Implications for cultured meat
Muscle stem cells (MuSCs) are essential for the growth, maintenance, and repair of skeletal
muscle. In the emerging area of cultured meat, meat products are manufactured with MuSCs …
muscle. In the emerging area of cultured meat, meat products are manufactured with MuSCs …
Maintaining bovine satellite cells stemness through p38 pathway
S Ding, GNM Swennen, T Messmer, M Gagliardi… - Scientific reports, 2018 - nature.com
Isolating and maintaining the appropriate stem cell for large scale cell culture is essential in
tissue engineering or food production. For bovine satellite cells an optimized isolation and …
tissue engineering or food production. For bovine satellite cells an optimized isolation and …
[HTML][HTML] ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion
T Eigler, G Zarfati, E Amzallag, S Sinha, N Segev… - Developmental cell, 2021 - cell.com
Myoblast fusion is essential for muscle development and regeneration. Yet, it remains poorly
understood how mononucleated myoblasts fuse with preexisting fibers. We demonstrate that …
understood how mononucleated myoblasts fuse with preexisting fibers. We demonstrate that …