Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Skeletal muscle: A review of molecular structure and function, in health and disease

K Mukund, S Subramaniam - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Decades of research in skeletal muscle physiology have provided multiscale insights into
the structural and functional complexity of this important anatomical tissue, designed to …

Diversity and versatility of p38 kinase signalling in health and disease

B Canovas, AR Nebreda - Nature reviews Molecular cell biology, 2021 - nature.com
The ability of cells to deal with different types of stressful situations in a precise and
coordinated manner is key for survival and involves various signalling networks. Over the …

A muscle stem cell support group: coordinated cellular responses in muscle regeneration

MN Wosczyna, TA Rando - Developmental cell, 2018 - cell.com
Skeletal muscle has an extraordinary regenerative capacity due to the activity of tissue-
specific muscle stem cells. Consequently, these cells have received the most attention in …

[HTML][HTML] Stem cell aging in skeletal muscle regeneration and disease

H Yamakawa, D Kusumoto, H Hashimoto… - International journal of …, 2020 - mdpi.com
Skeletal muscle comprises 30–40% of the weight of a healthy human body and is required
for voluntary movements in humans. Mature skeletal muscle is formed by multinuclear cells …

Function and inhibition of P38 MAP kinase signaling: Targeting multiple inflammation diseases

J Wang, Y Liu, Y Guo, C Liu, Y Yang, X Fan… - Biochemical …, 2024 - Elsevier
Inflammation is a natural host defense mechanism that protects the body from pathogenic
microorganisms. A growing body of research suggests that inflammation is a key factor in …

The role of the kynurenine pathway in the pathophysiology of frailty, sarcopenia, and osteoporosis

J Ballesteros, D Rivas, G Duque - Nutrients, 2023 - mdpi.com
Tryptophan is an essential nutrient required to generate vitamin B3 (niacin), which is mainly
involved in energy metabolism and DNA production. Alterations in tryptophan metabolism …

Bioprocessing technology of muscle stem cells: Implications for cultured meat

X Guan, J Zhou, G Du, J Chen - Trends in Biotechnology, 2022 - cell.com
Muscle stem cells (MuSCs) are essential for the growth, maintenance, and repair of skeletal
muscle. In the emerging area of cultured meat, meat products are manufactured with MuSCs …

Maintaining bovine satellite cells stemness through p38 pathway

S Ding, GNM Swennen, T Messmer, M Gagliardi… - Scientific reports, 2018 - nature.com
Isolating and maintaining the appropriate stem cell for large scale cell culture is essential in
tissue engineering or food production. For bovine satellite cells an optimized isolation and …

[HTML][HTML] ERK1/2 inhibition promotes robust myotube growth via CaMKII activation resulting in myoblast-to-myotube fusion

T Eigler, G Zarfati, E Amzallag, S Sinha, N Segev… - Developmental cell, 2021 - cell.com
Myoblast fusion is essential for muscle development and regeneration. Yet, it remains poorly
understood how mononucleated myoblasts fuse with preexisting fibers. We demonstrate that …