The role of inhibitory circuits in hippocampal memory processing

L Topolnik, S Tamboli - Nature Reviews Neuroscience, 2022 - nature.com
GABAergic inhibitory circuits play an essential role in coordinating various hippocampal
functions. Several decades of work dedicated to a thorough characterization of hippocampal …

[HTML][HTML] Hippocampal GABAergic interneurons and memory

A Tzilivaki, JJ Tukker, N Maier, P Poirazi, RP Sammons… - Neuron, 2023 - cell.com
One of the most captivating questions in neuroscience revolves around the brain's ability to
efficiently and durably capture and store information. It must process continuous input from …

[HTML][HTML] A transcriptomic axis predicts state modulation of cortical interneurons

S Bugeon, J Duffield, M Dipoppa, A Ritoux, I Prankerd… - Nature, 2022 - nature.com
Transcriptomics has revealed that cortical inhibitory neurons exhibit a great diversity of fine
molecular subtypes,,,,–, but it is not known whether these subtypes have correspondingly …

Local circuit amplification of spatial selectivity in the hippocampus

T Geiller, S Sadeh, SV Rolotti, H Blockus, B Vancura… - Nature, 2022 - nature.com
Local circuit architecture facilitates the emergence of feature selectivity in the cerebral
cortex. In the hippocampus, it remains unknown whether local computations supported by …

[HTML][HTML] Signatures of rapid plasticity in hippocampal CA1 representations during novel experiences

JB Priestley, JC Bowler, SV Rolotti, S Fusi, A Losonczy - Neuron, 2022 - cell.com
Neurons in the hippocampus exhibit a striking selectivity for specific combinations of sensory
features, forming representations that are thought to subserve episodic memory. Even …

Spatial transcriptomics: technical aspects of recent developments and their applications in neuroscience and cancer research

HE Park, SH Jo, RH Lee, CP Macks, T Ku… - Advanced …, 2023 - Wiley Online Library
Spatial transcriptomics is a newly emerging field that enables high‐throughput investigation
of the spatial localization of transcripts and related analyses in various applications for …

Hippocampal astrocytes encode reward location

A Doron, A Rubin, A Benmelech-Chovav, N Benaim… - Nature, 2022 - nature.com
Astrocytic calcium dynamics has been implicated in the encoding of sensory information,,,–,
and modulation of calcium in astrocytes has been shown to affect behaviour,,,–. However …

[HTML][HTML] Recruitment and inhibitory action of hippocampal axo-axonic cells during behavior

B Dudok, M Szoboszlay, A Paul, PM Klein, Z Liao… - Neuron, 2021 - cell.com
The axon initial segment of hippocampal pyramidal cells is a key subcellular compartment
for action potential generation, under GABAergic control by the" chandelier" or axo-axonic …

Inhibitory control of sharp-wave ripple duration during learning in hippocampal recurrent networks

B Vancura, T Geiller, A Grosmark, V Zhao… - Nature …, 2023 - nature.com
Recurrent excitatory connections in hippocampal regions CA3 and CA2 are thought to play
a key role in the generation of sharp-wave ripples (SWRs), electrophysiological oscillations …

Adaptive stimulus selection for consolidation in the hippocampus

S Terada, T Geiller, Z Liao, J O'Hare, B Vancura… - Nature, 2022 - nature.com
Associative memories guide behavioural adaptation by binding together outcome-predictive
sensory stimuli,. However, in a feature-rich environment, only a subset of stimuli may predict …