Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …

Biodegradable polymer based novel drug delivery systems have provided many avenues to
improve therapeutic efficacy and pharmacokinetic parameters of medicinal entities. Among …

The use of nanotechnology in medicine and more specifically drug delivery is set to spread
rapidly. Currently many substances are under investigation for drug delivery and more …

Encapsulation of small-molecule drugs in hydrophobic polymers or amphiphilic copolymers
has been extensively used for preparing polymeric nanoparticles (NPs). The loadings and …

Self-assembled nanomedicine holds great potential in cancer theragnostic. The structures
and dynamics of nanomedicine can be affected by a variety of non-covalent interactions, so …

Social and economic development has driven considerable scientific and engineering
efforts on the discovery, development, and utilization of polymers. Widespread reliance in …

Nanotechnology is expected to have an impact on all industries including semiconductors,
manufacturing, and biotechnology. Tools that provide the capability to characterize and …

This review summarizes the in vivo assessment preliminary, preclinical, and clinical of
chemotherapeutics derived from camptothecin or a derivative. Camptothecin is a naturally …

Micelles formed through the self-assembly of block copolymers have been widely used to
encapsulate highly hydrophobic drugs to increase their effective solubility. However, this …

The application of nanotechnology to medicine, commonly referred to as 'nanomedicine',
has the potential to transform our approach to human health and disease. Research at the …