In healthcare, the development and deployment of insufficiently fair systems of artificial
intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models …

Despite increasing numbers of regulatory approvals, deep learning-based computational
pathology systems often overlook the impact of demographic factors on performance …

Simple Summary Triple Negative Breast Cancer (TNBC) comprises approximately 15–20%
of all breast cancer (BC) cases, is often diagnosed at an advanced stage, and is generally …

Abstract This is the American Cancer Society's biennial update of statistics on breast cancer
among women based on high‐quality incidence and mortality data from the National Cancer …

Cancer genomes from patients with African (AFR) ancestry have been poorly studied in
clinical research. We leverage two large genomic cohorts to investigate the relationship …

Differences in the average age at cancer diagnosis are observed across countries. We
therefore aimed to assess international variation in the median age at diagnosis of common …

Background Treatment with regorafenib, a multiple-kinase inhibitor, to manage metastatic
colorectal cancers (mCRCs) shows a modest improvement in overall survival but is …

Single-nucleus analysis allows robust cell-type classification and helps to establish
relationships between chromatin accessibility and cell-type-specific gene expression. Here …

Cancer incidence and mortality rates can vary widely among different racial and ethnic
groups, attributed to a complex interplay of genetic, environmental and social factors …

The biologic basis of genetic ancestry-dependent variability in disease incidence and
outcome is just beginning to be explored. We recently reported enrichment of a population of …