Microbial steroid transformations: current state and prospects
MV Donova, OV Egorova - Applied microbiology and biotechnology, 2012 - Springer
Studies of steroid modifications catalyzed by microbial whole cells represent a well-
established research area in white biotechnology. Still, advances over the last decade in …
established research area in white biotechnology. Still, advances over the last decade in …
New insights on steroid biotechnology
Nowadays steroid manufacturing occupies a prominent place in the pharmaceutical industry
with an annual global market over $10 billion. The synthesis of steroidal active …
with an annual global market over $10 billion. The synthesis of steroidal active …
[BOOK][B] Modern oxidation methods
JE Bäckvall - 2011 - books.google.com
While rust is an unwanted oxidation reaction, there are also many other useful oxidation
reactions that are extremely important and number among the most commonly used …
reactions that are extremely important and number among the most commonly used …
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design
The cytochrome P450 enzyme lanosterol 14α-demethylase (LDM) is the target of the azole
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
antifungals used widely in medicine and agriculture as prophylaxis or treatments of …
Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris
Abstract The sesquiterpenoid (+)-nootkatone is a highly demanded and highly valued aroma
compound naturally found in grapefruit, pummelo or Nootka cypress tree. Extraction of (+) …
compound naturally found in grapefruit, pummelo or Nootka cypress tree. Extraction of (+) …
Recombinant production of eukaryotic cytochrome P450s in microbial cell factories
J Hausjell, H Halbwirth, O Spadiut - Bioscience reports, 2018 - portlandpress.com
Cytochrome P450s (P450s) comprise one of the largest known protein families. They occur
in every kingdom of life and catalyze essential reactions, such as carbon source …
in every kingdom of life and catalyze essential reactions, such as carbon source …
Functional expression of eukaryotic cytochrome P450s in yeast
L Jiang, L Huang, J Cai, Z Xu… - Biotechnology and …, 2021 - Wiley Online Library
Cytochrome P450 enzymes (P450s) are a superfamily of heme‐thiolate proteins widely
existing in various organisms. Due to their key roles in secondary metabolism, degradation …
existing in various organisms. Due to their key roles in secondary metabolism, degradation …
Heme-iron oxygenases: powerful industrial biocatalysts?
MK Julsing, S Cornelissen, B Bühler… - Current opinion in chemical …, 2008 - Elsevier
Are cytochrome P450 enzymes powerful industrial biocatalysts? Next to market demands,
well-defined enzyme functionalities and process parameters allow generalizations on the …
well-defined enzyme functionalities and process parameters allow generalizations on the …
Guidelines for development and implementation of biocatalytic P450 processes
MT Lundemo, JM Woodley - Applied microbiology and biotechnology, 2015 - Springer
Biocatalytic reactions performed by cytochrome P450 monooxygenases are interesting in
pharmaceutical research since they are involved in human drug metabolism. Furthermore …
pharmaceutical research since they are involved in human drug metabolism. Furthermore …
Differential regulation by heat stress of novel cytochrome P450 genes from the dinoflagellate symbionts of reef-building corals
Exposure to heat stress has been recognized as one of the major factors leading to the
breakdown of the coral-alga symbiosis and coral bleaching. Here, we describe the presence …
breakdown of the coral-alga symbiosis and coral bleaching. Here, we describe the presence …