Enormous studies have corroborated that long non-coding RNAs (lncRNAs) extensively
participate in crucial physiological processes such as metabolism and immunity, and are …

Over the last two decades, significant advances have been made using genetic engineering
technology to modify genes from various exotic origins and introduce them into plants to …

With the first RNA interference (RNAi) drug (ONPATTRO (patisiran)) on the market, we
witness the RNAi therapy field reaching a critical turning point, when further improvements in …

While small interfering RNA (siRNA) technology has become a powerful tool that can enable
cancer-specific gene therapy, its translation to the clinic is still hampered by the inability of …

Self‐assembly of small interfering RNA (siRNA) with a block copolymer featuring
guanidinium and zwitterion functionalized blocks generates core‐shell‐like nanovectors that …

RNA-based oligonucleotide therapeutics are revolutionizing drug development for disease
treatment. This class of therapeutics differs from small molecules and protein therapeutics in …

HIV/AIDS is a chronic and debilitating disease that cannot be cured with current antiretroviral
drugs. While combinatorial antiretroviral therapy (cART) can potently suppress HIV-1 …

Little is known about the function of most non-coding RNAs (ncRNAs). The majority of long
ncRNAs (lncRNAs) is expressed at very low levels and it is a matter of intense debate …

The capacity for language is one of the key features underlying the complexity of human
cognition and its evolution. However, little is known about the neurobiological mechanisms …

Parkinson's disease (PD) is one of the most common neurodegenerative disorders that
manifest various motor and nonmotor symptoms. Although currently available therapies can …