Inflammation and tumor progression: signaling pathways and targeted intervention

H Zhao, L Wu, G Yan, Y Chen, M Zhou… - Signal transduction and …, 2021 - nature.com
Cancer development and its response to therapy are regulated by inflammation, which
either promotes or suppresses tumor progression, potentially displaying opposing effects on …

Oxidative stress in intervertebral disc degeneration: molecular mechanisms, pathogenesis and treatment

Y Wang, H Cheng, T Wang, K Zhang, Y Zhang… - Cell …, 2023 - Wiley Online Library
Low back pain (LBP) is a leading cause of labour loss and disability worldwide, and it also
imposes a severe economic burden on patients and society. Among symptomatic LBP …

Inflammatory response of nanoparticles: mechanisms, consequences, and strategies for mitigation

M Summer, R Ashraf, S Ali, H Bach, S Noor, Q Noor… - Chemosphere, 2024 - Elsevier
Numerous nano-dimensioned materials have been generated as a result of several
advancements in nanoscale science such as metallic nanoparticles (mNPs) which have …

Dysregulation of immunity by cigarette smoking promotes inflammation and cancer: a review

Y Liu, L Lu, H Yang, X Wu, X Luo, J Shen, Z **ao… - Environmental …, 2023 - Elsevier
Smoking is a serious global health issue. Cigarette smoking contains over 7000 different
chemicals. The main harmful components include nicotine, acrolein, aromatic hydrocarbons …

Dissecting the crosstalk between Nrf2 and NF-κB response pathways in drug-induced toxicity

W Gao, L Guo, Y Yang, Y Wang, S **a… - Frontiers in cell and …, 2022 - frontiersin.org
Nrf2 and NF-κB are important regulators of the response to oxidative stress and
inflammation in the body. Previous pharmacological and genetic studies have confirmed …

Inflammatory bowel disease and risk of colorectal cancer: An overview from pathophysiology to pharmacological prevention

M Lucafò, D Curci, M Franzin, G Decorti… - Frontiers in …, 2021 - frontiersin.org
Increased risk of colorectal cancer (CRC) in inflammatory bowel disease (IBD) patients has
been attributed to long-standing chronic inflammation, with the contribution of genetic …

The potential of dandelion in the fight against gastrointestinal diseases: A review

Y Li, Y Chen, D Sun-Waterhouse - Journal of ethnopharmacology, 2022 - Elsevier
Abstract Ethnopharmacological relevance Dandelion (Taraxacum officinale Weber ex FH
Wigg.), as a garden weed grown globally, has long been consumed as a therapeutic herb …

Gut dysbiosis in patients with chronic pain: A systematic review and meta-analysis

L Goudman, T Demuyser, JG Pilitsis, M Billot… - Frontiers in …, 2024 - frontiersin.org
Introduction Recent evidence supports the contribution of gut microbiota dysbiosis to the
pathophysiology of rheumatic diseases, neuropathic pain, and neurodegenerative …

Helicobacter pylori–induced RASAL2 through activation of nuclear Factor-κB promotes gastric tumorigenesis via β-catenin signaling Axis

L Cao, S Zhu, H Lu, M Soutto, N Bhat, Z Chen, D Peng… - Gastroenterology, 2022 - Elsevier
Background & aims Helicobacter pylori infection is the predominant risk factor for gastric
cancer. RAS protein activator like 2 (RASAL2) is considered a double-edged sword in …

An emerging strategy: probiotics enhance the effectiveness of tumor immunotherapy via mediating the gut microbiome

S Jiang, W Ma, C Ma, Z Zhang, W Zhang, J Zhang - Gut microbes, 2024 - Taylor & Francis
The occurrence and progression of tumors are often accompanied by disruptions in the gut
microbiota. Inversely, the impact of the gut microbiota on the initiation and progression of …