Background: An ENDO-European Reference Network (ERN) initiative was launched that
was endorsed by the European Society for Pediatric Endocrinology and the European …

Detection by newborn screening (NBS) and treatment of babies with congenital
hypothyroidism (CH) has largely eliminated the intellectual disability caused by this disorder …

Untreated congenital hypothyroidism (CH) leads to intellectual disabilities. Prompt diagnosis
by newborn screening (NBS) leading to early and adequate treatment results in grossly …

Objective: The aim was to formulate practice guidelines for the diagnosis and management
of congenital hypothyroidism (CH). Evidence: A systematic literature search was conducted …

Context: Congenital hypothyroidism (CH) is reportedly increasing in the United States,
possibly reflecting changes in screening methods. In Québec, the same initial TSH cutoff (15 …

Abstract Congenital hypothyroidism, occurring in 1: 3000 newborns, is one of the most
common preventable causes of mental retardation. Neurodevelopmental outcome is …

Inborn errors of metabolism (IEMs) are a group of inherited diseases with variable
incidences. IEMs are caused by disrupting enzyme activities in specific metabolic pathways …

Central congenital hypothyroidism (CH) is defined as thyroid hormone (TH) deficiency at
birth due to insufficient stimulation by the pituitary of the thyroid gland. The incidence of …

Congenital hypothyroidism occurs in approximately 1 in 2000 newborns and can have
devastating neurodevelopmental consequences if not detected and treated promptly. While …

Although newborn screening has virtually eradicated mental retardation due to congenital
hypothyroidism in parts of the world, new information continues to accumulate and new …