Biomedical applications of calixarenes: state of the art and perspectives

YC Pan, XY Hu, DS Guo - Angewandte Chemie International …, 2021 - Wiley Online Library
Calixarenes (CAs), representing the third generation of supramolecular hosts and one of the
most widely studied macrocyclic scaffolds, offer (almost) unlimited structure and application …

Biological applications of functionalized calixarenes

SB Nimse, T Kim - Chemical Society Reviews, 2013 - pubs.rsc.org
The functionalized calixarene derivatives exhibit remarkable properties towards organic and
bioorganic molecules. However, the ability of calixarene derivatives to form stable …

Supramolecular chemistry targeting proteins

S van Dun, C Ottmann, LG Milroy… - Journal of the American …, 2017 - ACS Publications
The specific recognition of protein surface elements is a fundamental challenge in the life
sciences. New developments in this field will form the basis of advanced therapeutic …

Small molecule targeting Cdc42–intersectin interaction disrupts Golgi organization and suppresses cell motility

A Friesland, Y Zhao, YH Chen… - Proceedings of the …, 2013 - National Acad Sciences
Signaling through the Rho family of small GTPases has been intensely investigated for its
crucial roles in a wide variety of human diseases. Although RhoA and Rac1 signaling …

Applications of calixarenes in cancer chemotherapy: facts and perspectives

A Yousaf, SA Hamid, NM Bunnori… - … design, development and …, 2015 - Taylor & Francis
Research on the therapeutic applications of calixarene derivatives is an emerging area of
interest. The anticancer activity of various functionalized calixarenes has been reported by …

Calixarenes in bio-medical researches

RV Rodik, VI Boyko… - Current Medicinal …, 2009 - ingentaconnect.com
Application of calixarene derivatives in bio-medical researches is reviewed in this article.
Antiviral, bactericidal, antithrombothic, antituberculosis, anticancer activity as well as specific …

Calixarenes as new platforms for drug design

 de Fátima, SA Fernandes… - Current Drug Discovery …, 2009 - ingentaconnect.com
Calixarenes, macrocyclic compounds of phenolic units linked by methylene groups at the 2,
6-positions, present some of the requirements to serve as platforms for the design and …

Host-Guest Complexation of Oxaliplatin and Para-Sulfonatocalix[n]Arenes for Potential Use in Cancer Therapy

SA Fahmy, F Ponte, IM Fawzy, E Sicilia, U Bakowsky… - Molecules, 2020 - mdpi.com
P-sulfonatocalix [n] arenes have demonstrated a great potential for encapsulation of
therapeutic drugs via host-guest complexation to improve solubility, stability, and …

Boron-containing small molecules as anti-inflammatory agents

T Akama, YK Zhang, CZ Ding, JJ Plattner… - US Patent …, 2011 - Google Patents
2009-07-29 Assigned to ANACOR PHARMACEUTICALS, INC. reassignment ANACOR
PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Design, synthesis and evaluation of calix [4] arene-based carbonyl amide derivatives with antitumor activities

L An, C Wang, YG Zheng, JD Liu, TH Huang - European Journal of …, 2021 - Elsevier
Calixarenes, with potential functionalization on the upper and lower rim, have been explored
in recent years for the design and construction of anticancer agents in the field of drugs and …