Alzheimer's disease: an updated overview of its genetics
J Andrade-Guerrero, A Santiago-Balmaseda… - International journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease in the world. It is
classified as familial and sporadic. The dominant familial or autosomal presentation …
classified as familial and sporadic. The dominant familial or autosomal presentation …
Mesoporous silica and organosilica nanoparticles: physical chemistry, biosafety, delivery strategies, and biomedical applications
Predetermining the physico‐chemical properties, biosafety, and stimuli‐responsiveness of
nanomaterials in biological environments is essential for safe and effective biomedical …
nanomaterials in biological environments is essential for safe and effective biomedical …
Exposure to air pollution as a potential contributor to cognitive function, cognitive decline, brain imaging, and dementia: a systematic review of epidemiologic research
Background Dementia is a devastating condition typically preceded by a long prodromal
phase characterized by accumulation of neuropathology and accelerated cognitive decline …
phase characterized by accumulation of neuropathology and accelerated cognitive decline …
Drugs in clinical trials for Alzheimer's disease: the major trends
SO Bachurin, EV Bovina… - Medicinal research …, 2017 - Wiley Online Library
Alzheimer's disease (AD) is characterized by a chronic and progressive neurodegenerative
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …
process resulting from the intracellular and extracellular accumulation of fibrillary proteins …
[HTML][HTML] Metallobiology and therapeutic chelation of biometals (copper, zinc and iron) in Alzheimer's disease: Limitations, and current and future perspectives
Background Alzheimer's disease (AD) is the most prevalent cause of cognitive impairment
and dementia worldwide. The pathobiology of the disease has been studied in the form of …
and dementia worldwide. The pathobiology of the disease has been studied in the form of …
An assessment of paralinguistic acoustic features for detection of Alzheimer's dementia in spontaneous speech
Speech analysis could provide an indicator of Alzheimer's disease and help develop clinical
tools for automatically detecting and monitoring disease progression. While previous studies …
tools for automatically detecting and monitoring disease progression. While previous studies …
Tau protein and its role in blood–brain barrier dysfunction
A Michalicova, P Majerova, A Kovac - Frontiers in molecular …, 2020 - frontiersin.org
The blood–brain barrier (BBB) plays a crucial role in maintaining the specialized
microenvironment of the central nervous system (CNS). In aging, the stability of the BBB …
microenvironment of the central nervous system (CNS). In aging, the stability of the BBB …
Novel approaches for the treatment of Alzheimer's and Parkinson's disease
Neurodegenerative disorders affect around one billion people worldwide. They can arise
from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is …
from a combination of genomic, epigenomic, metabolic, and environmental factors. Aging is …
Zebrafish: an emerging real-time model system to study Alzheimer's disease and neurospecific drug discovery
Zebrafish (Danio rerio) is emerging as an increasingly successful model for translational
research on human neurological disorders. In this review, we appraise the high degree of …
research on human neurological disorders. In this review, we appraise the high degree of …
Role of the extracellular matrix in Alzheimer's disease
Y Sun, S Xu, M Jiang, X Liu, L Yang, Z Bai… - Frontiers in aging …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease with complex pathological
characteristics, whose etiology and pathogenesis are still unclear. Over the past few …
characteristics, whose etiology and pathogenesis are still unclear. Over the past few …