Classic psychedelics, such as LSD, psilocybin, and the DMT-containing beverage
ayahuasca, show some potential to treat depression, anxiety, and addiction. Importantly …

The mystical experience is a potential psychological mechanism to influence outcome in
psychedelic therapy. It includes features such as oceanic boundlessness, ego dissolution …

Psychedelics are a broad class of drugs defined by their ability to induce an altered state of
consciousness,. These drugs have been used for millennia in both spiritual and medicinal …

Importance Although classic psychedelic medications have shown promise in the treatment
of alcohol use disorder (AUD), the efficacy of psilocybin remains unknown. Objective To …

Background: Preliminary data suggest that psilocybin-assisted treatment produces
substantial and rapid antidepressant effects in patients with major depressive disorder …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Psilocybin has shown promise for the treatment of mood disorders, which are often
accompanied by cognitive dysfunction including cognitive rigidity. Recent studies have …

Background Psychedelic therapy shows promise for Major Depressive Disorder, especially
when treatment-resistant, as well as life-threatening illness distress. The objective of this …

Importance Major depressive disorder (MDD) is a substantial public health burden, but
current treatments have limited effectiveness and adherence. Recent evidence suggests that …

Classic psychedelics produce altered states of consciousness that individuals often interpret
as meaningful experiences. Across a number of human studies, when the participant-rated …