An overview on taxol production technology and its applications as anticancer agent

A Sharma, SK Bhatia, A Banyal, I Chanana… - Biotechnology and …, 2022 - Springer
Cancer is undeniably a major health risk factor that is growing rapidly globally despite
promising medicinal and pharmaceutical development. Treatment of cancer remains an …

Computational and synthetic biology approaches for the biosynthesis of antiviral and anticancer Terpenoids from Bacillus subtilis

V Shukla, A Runthala, VS Rajput… - Medicinal …, 2022 - ingentaconnect.com
Recent advancements in medicinal research have identified several antiviral and anticancer
terpenoids that are usually deployed as a source of flavor, fragrances and pharmaceuticals …

Excavating the functionally crucial active-site residues of the DXS protein of Bacillus subtilis by exploring its closest homologues

A Runthala, TH Sai, V Kamjula, SC Phulara… - Journal of Genetic …, 2020 - Springer
Background To achieve a high yield of terpenoid-based therapeutics, 1-deoxy-d-xylulose-5-
phosphate (DXP) pathway has been significantly exploited for the production of downstream …

Probabilistic divergence of a template-based modelling methodology from the ideal protocol

A Runthala - Journal of Molecular Modeling, 2021 - Springer
Protein structural information is essential for the detailed map** of a functional protein
network. For a higher modelling accuracy and quicker implementation, template-based …

Biomimetic Approach for the Controlled Drug Delivery through 3D Bioactive Scaffolds: A Novel Strategy for Tissue Engineering Applications

A Chandana, SP Mallick, BN Singh, A Anand… - Drugs and a …, 2023 - Springer
A suitable drug delivery system may accelerate the growth and repair of a new tissue. Small-
molecule chemicals, proteins, peptides, cytokines, etc. typically known as drugs have a …

Current strategic limitations of phylogenetic tools badly impact the inference of an evolutionary tree

S Nasika, A Runthala - bioRxiv, 2021 - biorxiv.org
For drawing an evolutionary relationship among several protein sequences, the
phylogenetic tree is usually constructed through maximum likelihood-based algorithms. To …

Plant Phytochemicals as Potential Therapeutics in Neurological Disorders

P Prabhakar, A Kumar, M Banerjee - Plant-based Foods and their … - taylorfrancis.com
Neurological disorders are abnormal conditions in the nervous system. A variety of
symptoms can be caused by structural, metabolic, or electrical abnormalities in the brain …