Mitophagy receptors and mediators: therapeutic targets in the management of cardiovascular ageing
A Ajoolabady, H Aslkhodapasandhokmabad… - Ageing Research …, 2020 - Elsevier
Mitophagy serves as a cardinal regulator in the maintenance of mitochondrial integrity,
function, and cardiovascular homeostasis, through the fine control and governance of …
function, and cardiovascular homeostasis, through the fine control and governance of …
Mitochondrial dynamics, mitophagy, and mitochondria–endoplasmic reticulum contact sites crosstalk under hypoxia
S Wang, J Tan, Y Miao, Q Zhang - Frontiers in cell and developmental …, 2022 - frontiersin.org
Mitochondria are double membrane organelles within eukaryotic cells, which act as cellular
power houses, depending on the continuous availability of oxygen. Nevertheless, under …
power houses, depending on the continuous availability of oxygen. Nevertheless, under …
[HTML][HTML] Mitochondria pleiotropism in stem cell senescence: Mechanisms and therapeutic approaches
C Mas-Bargues - Free Radical Biology and Medicine, 2023 - Elsevier
Aging is a complex biological process characterized by a progressive decline in cellular and
tissue function, ultimately leading to organismal aging. Stem cells, with their regenerative …
tissue function, ultimately leading to organismal aging. Stem cells, with their regenerative …
The multifaceted role of cell cycle regulators in the coordination of growth and metabolism
K Huber, A Mestres‐Arenas, L Fajas… - The FEBS …, 2021 - Wiley Online Library
Adapting to changes in nutrient availability and environmental conditions is a fundamental
property of cells. This adaptation requires a multi‐directional coordination between …
property of cells. This adaptation requires a multi‐directional coordination between …
Advances in understanding mechanisms underlying mitochondrial structure and function damage by ozone
T Wu, Z Li, Y Wei - Science of The Total Environment, 2023 - Elsevier
Mitochondria are double-membraned organelles found in eukaryotic cells. The integrity of
mitochondrial structure and function determines cell destiny. Mitochondria are also the …
mitochondrial structure and function determines cell destiny. Mitochondria are also the …
The role of mitochondrial dynamics and mitotic fission in regulating the cell cycle in cancer and pulmonary arterial hypertension: implications for dynamin-related …
Mitochondria, which generate ATP through aerobic respiration, also have important
noncanonical functions. Mitochondria are dynamic organelles, that engage in fission …
noncanonical functions. Mitochondria are dynamic organelles, that engage in fission …
Cu (I)/Cu (II) released by Cu nanoparticles revealed differential cellular toxicity related to mitochondrial dysfunction
Cu-based nanoparticles (NPs) have been increasingly fabricated, and different Cu species
(ie, Cu+ and Cu2+) of these NPs are tuned to achieve differential physicochemical …
(ie, Cu+ and Cu2+) of these NPs are tuned to achieve differential physicochemical …
The aging of ER-mitochondria communication: A journey from undifferentiated to aged cells
P Morgado-Cáceres, G Liabeuf, X Calle… - Frontiers in Cell and …, 2022 - frontiersin.org
The complex physiology of eukaryotic cells requires that a variety of subcellular organelles
perform unique tasks, even though they form highly dynamic communication networks. In the …
perform unique tasks, even though they form highly dynamic communication networks. In the …
Rapamycin ameliorates defects in mitochondrial fission and mitophagy in glioblastoma cells
P Lenzi, R Ferese, F Biagioni, F Fulceri… - International Journal of …, 2021 - mdpi.com
Glioblastoma (GBM) cells feature mitochondrial alterations, which are documented and
quantified in the present study, by using ultrastructural morphometry. Mitochondrial …
quantified in the present study, by using ultrastructural morphometry. Mitochondrial …
[HTML][HTML] Extracellular matrix stiffness regulates mitochondrial dynamics through PINCH-1-and kindlin-2-mediated signalling
K Chen, Y Wang, X Deng, L Guo, C Wu - Current Research in Cell Biology, 2021 - Elsevier
Proper control of mitochondrial morphology is crucial for many vital cellular processes
including energy production, cell cycle and apoptosis. We show here that extracellular …
including energy production, cell cycle and apoptosis. We show here that extracellular …