Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

Small molecule drug discovery has been propelled by the continual development of novel
scientific methodologies to occasion therapeutic advances. Although established …

Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and
selected analytes allow phenotypic characterization and serve as biomarkers, respectively …

Mass spectrometry is a central technology in the life sciences, providing our most
comprehensive account of the molecular inventory of the cell. In parallel with developments …

When non-mass spectrometrists are talking about mass spectrometry it rather often sounds
as if they were telling a story out of Poe's Tales of Mystery and Imagi-tion. Indeed, mass …

Protein glycosylation is an important post-translational modification. It is a feature that
enhances the functional diversity of proteins and influences their biological activity. A wide …

The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …

The analysis of peptides and proteins as well as the grander scope of proteomics (large
scale study of proteins) has been advanced by the development of a versatile array of ion …

MS/MS currently serves as the workhorse for metabolomics. Structural identification is
extremely important to correlate statistical variables to biochemical functions and …

Over the past decade, mass spectrometry has been revolutionized by access to instruments
of increasingly high mass-resolving power. For small molecules up to∼ 400 Da (eg, drugs …