The biology, function, and biomedical applications of exosomes
BACKGROUND All cells, prokaryotes and eukaryotes, release extracellular vesicles (EVs)
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
as part of their normal physiology and during acquired abnormalities. EVs can be broadly …
Exosomes: the next generation of endogenous nanomaterials for advanced drug delivery and therapy
Abstract Development of functional nanomaterials is of great importance and significance for
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
advanced drug delivery and therapy. Nevertheless, exogenous nanomaterials have a great …
Exosomal therapy—A new frontier in regenerative medicine
S Muthu, A Bapat, R Jain, N Jeyaraman… - Stem cell …, 2021 - pmc.ncbi.nlm.nih.gov
The recent advances in translational and nanomedicine have paved the way for develo**
the targeted drug delivery system at a greater pace among global researchers. On par with …
the targeted drug delivery system at a greater pace among global researchers. On par with …
Advancing personalized medicine through the application of whole exome sequencing and big data analytics
There is a growing attention toward personalized medicine. This is led by a fundamental
shift from the 'one size fits all'paradigm for treatment of patients with conditions or …
shift from the 'one size fits all'paradigm for treatment of patients with conditions or …
Exosome: a significant nano-scale drug delivery carrier
H Peng, W Ji, R Zhao, J Yang, Z Lu, Y Li… - Journal of Materials …, 2020 - pubs.rsc.org
In recent years, due to the limitations of the nature of therapeutic agents, many synthetic
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
nano-delivery systems have emerged to enhance the efficacy of drugs. Extracellular vesicles …
Diagnostic potential of exosomal extracellular vesicles in oncology
Liquid biopsy can detect circulating cancer cells or tumor cell-derived DNA at various stages
of cancer. The fluid from these biopsies contains extracellular vesicles (EVs), such as …
of cancer. The fluid from these biopsies contains extracellular vesicles (EVs), such as …
[HTML][HTML] Roles of extracellular HSPs as biomarkers in immune surveillance and immune evasion
Extracellular heat shock proteins (ex-HSPs) have been found in exosomes, oncosomes,
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …
membrane surfaces, as well as free HSP in cancer and various pathological conditions, also …
[HTML][HTML] New approaches to SCLC therapy: from the laboratory to the clinic
The outcomes of patients with SCLC have not yet been substantially impacted by the
revolution in precision oncology, primarily owing to a paucity of genetic alterations in …
revolution in precision oncology, primarily owing to a paucity of genetic alterations in …
3D cell culture stimulates the secretion of in vivo like extracellular vesicles
For studying cellular communications ex-vivo, a two-dimensional (2D) cell culture model is
currently used as the “gold standard”. 2D culture models are also widely used in the study of …
currently used as the “gold standard”. 2D culture models are also widely used in the study of …
Breast cancer, screening and diagnostic tools: All you need to know
Breast cancer is one of the most frequent malignancies among women worldwide. Methods
for screening and diagnosis allow health care professionals to provide personalized …
for screening and diagnosis allow health care professionals to provide personalized …