Comprehensive review on different analytical techniques for HIV 1-integrase inhibitors: Raltegravir, Dolutegravir, Elvitegravir and Bictegravir

P Jain, A Thota, PK Saini… - Critical Reviews in …, 2024 - Taylor & Francis
The advent of HIV-Integrase inhibitors (IN) has marked a significant impact on the lives of
HIV patients. Since the launch of the first anti retro-viral drug “Azidothymidine” to the recent …

[HTML][HTML] Fruit peels that unlock curative potential: Determination of biomedical application and bioactive compounds

VN Punitha, S Vijayakumar, M Nilavukkarasi… - South African Journal of …, 2022 - Elsevier
Control of multi drug resistant bacteria and their infection rate is a threat for biomedical and
clinical research. Citrus fruits have proven effective against incurable bacterial infections …

[HTML][HTML] Development and validation of a stability-indicating RP-HPLC method for the simultaneous estimation of bictegravir, emtricitabine, and tenofovir alafenamide …

T Attaluri, S Ganapaty… - Turkish Journal of …, 2021 - ncbi.nlm.nih.gov
Objectives: The focal intent of the current research work is to develop and validate a novel
and reliable stability-indicating reverse-phase high performance liquid chromatographic …

Assessment of the greenness of new stability indicating micellar UPLC and HPTLC methods for determination of tenofovir alafenamide in dosage forms

NS Said, ZA Nasr… - Journal of …, 2021 - academic.oup.com
In this study, a green stability indicating chromatographic methods were developed and
validated for the quantitative determination of tenofovir alafenamide in the presence of its …

Study on the hydrolytic degradation behaviour of bictegravir by LC-PDA-Q/TOF-MS/MS NMR and in silico toxicity assessment

SR Dannarm, D Harini, GN Reddy, N Ali… - Journal of Pharmaceutical …, 2024 - Elsevier
Forced degradation studies provide rapid access to degradation products (DPs), where
structural characterization and assessment of their potential toxicity are vital for …

[PDF][PDF] Bio-analytical method development and validation for simultaneous determination of bictegravir, emtricitabine, and tenofovir alafenamide fumarate in human …

A Tanuja, S Ganapaty - Indian Journal of Pharmaceutical Education and …, 2022 - ijper.org
Aim: The current method was developed as a novel and reliable quantitative liquid
chromatography-mass (tandem) spectrometry (LC-MS/MS) method for the estimation of …

Forced degradation studies and development of RP-HPLC method for related substances of Tenofovir alafenamide in tablet dosage form

BN Patel, HJ Vekaria - Analytical Chemistry Letters, 2023 - Taylor & Francis
The development and validation of an easy and rapid stability-indicating RP-HPLC
technique for Tenofovir alafenamide and its impurities. In this newly developed method …

[HTML][HTML] Development of LC/LCMS method for estimation of impurities in anti-HIV drug (Bictegravir) using Analytical Quality by Design (AQbD) approach

DK VEMURI, R GUNDLA, JK RAGHUPATHI… - Chinese Journal of …, 2025 - Elsevier
Abstract Analytical Quality by Design (AQbD) was used to construct stability indicating linked
compounds using the HPLC technique of an anti-human immunodeficiency virus (anti-HIV) …

Green stability indicating UV-spectrophotometric techniques for estimation of tenofovir alafenamide in bulk form and dosage forms

N Said, Z Nasr, S Abd El Razeq - … International Journal of …, 2021 - aijpms.journals.ekb.eg
Four simple, precise and sensitive UV-spectrophotometric procedures were achieved for
estimation of tenofovir alafenamide in the presence of its alkaline degradate. Dual …

[HTML][HTML] Application of Reversed-Phase HPLC Method for the Simultaneous Determination of Lenacapavir and Bictegravir in Tablets Dosage Form

A Madhavi, M Srinivas, N Gupta - Journal of Young Pharmacists, 2024 - jyoungpharm.org
Background Human Immunodeficiency Virus is a debilitating viral infection that
compromises the immune system, rendering individuals vulnerable to opportunistic …