Granule cells (GCs) are the most numerous cell type in the cerebellum and indeed, in the
brain: at least 99% of all cerebellar neurons are granule cells. In this review article, we first …

Zinc finger E-box binding homeobox 1 (ZEB1) is a master modulator of the epithelial–
mesenchymal transition (EMT), a process whereby epithelial cells undergo a series of …

Purpose of the review: The synchronic development of vascular and nervous systems is
orchestrated by common molecules that regulate the communication between both systems …

Current protocols for producing cerebellar neurons from human pluripotent stem cells
(hPSCs) often rely on animal co-culture and mostly exist as monolayers, limiting their …

Physical activity and cognitive challenge are established non-invasive methods to induce
comprehensive brain activation and thereby improve global brain function including mood …

Neuroinflammation is regarded as a vital pathological process in spinal cord injury (SCI),
which removes damaged tissue, secretes cytokines, and facilitates regeneration …

Mammalian cells respond to insufficient oxygen through transcriptional regulators called
hypoxia-inducible factors (HIFs). Although transiently protective, prolonged HIF activity …

Preface Executive functions, learning, attention, and processing speed are imperative facets
of cognitive performance, affected in neuropsychiatric disorders. In clinical studies on …

Cells store excess energy in the form of lipid droplets (LDs), a specialized sub-compartment
of the endoplasmic reticulum (ER) network. The lipodystrophy protein seipin is a key player …

The well-organized cerebellar structures and neuronal networks are likely crucial for their
functions in motor coordination, motor learning, cognition, and emotion. Such cerebellar …