The blood-brain barrier (BBB) has been a great hurdle for brain drug delivery. The BBB in
healthy brain is a diffusion barrier essential for protecting normal brain function by impeding …

Intracerebral haemorrhage (ICH) is the most lethal subtype of stroke but currently lacks
effective treatment. Microglia are among the first non-neuronal cells on the scene during the …

Intracerebral hemorrhage (ICH) is a common and severe cerebrovascular disease that has
high mortality. Few survivors achieve self-care. Currently, patients receive only symptomatic …

The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …

Intracerebral hemorrhage (ICH) remains the most lethal type of stroke, and effective clinical
therapies that can speed up hematoma resolution after ICH are still lacking. While the …

Although intracerebral hemorrhage (ICH) is a devastating disease worldwide, the pathologic
changes in ultrastructure during the acute and chronic phases of ICH are poorly described …

White matter fiber tracking using diffusion magnetic resonance imaging (dMRI) provides a
noninvasive approach to map brain connections, but improving anatomical accuracy has …

Diabetic hyperglycemia aggravates the prognosis of intracerebral hemorrhagic stroke (ICH)
in the clinic. In addition to hematoma expansion and increased inflammation, how diabetic …

Salvianolic acid B (SalB), a natural polyphenolic compound extracted from the herb of Salvia
miltiorrhiza, possesses antioxidant and neuroprotective properties and has been shown to …

Differential diagnosis of brain lesion pathologies is complex, but it is nevertheless crucial for
appropriate clinical management. Advanced imaging methods, including diffusion-weighted …