Recent advances in bioactive pyrazoles
Pyrazole is a five membered and two-nitrogen containing heterocyclic ring. These structures
have been investigated in the development of novel compounds with hypoglycemic …
have been investigated in the development of novel compounds with hypoglycemic …
Anti-cancer nitrogen-containing heterocyclic compounds
Cancer is one of the leading causes of death worldwide. Mutation of the cell regulates genes
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …
and protein causing cancer. Surgery, radiotherapy, and the use of anticancer agents are the …
Recent advancement in drug design and discovery of pyrazole biomolecules as cancer and inflammation therapeutics
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti …
Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial …
The control of antimicrobial resistance (AMR) seems to have come to a dead end. The major
consequences of the use and abuse of antibacterial drugs are the development of resistant …
consequences of the use and abuse of antibacterial drugs are the development of resistant …
Recent progress in anticancer agents incorporating pyrazole scaffold
S Mor, M Khatri, R Punia… - Mini Reviews in Medicinal …, 2022 - benthamdirect.com
The search for new anticancer agents is considered a dynamic field of medicinal chemistry.
In recent years, the synthesis of compounds with anticancer potential has increased and a …
In recent years, the synthesis of compounds with anticancer potential has increased and a …
Development of Biotechnological Photosensitizers for Photodynamic Therapy: Cancer Research and Treatment—From Benchtop to Clinical Practice
M Aires-Fernandes, R Botelho Costa… - Molecules, 2022 - mdpi.com
Photodynamic therapy (PDT) is a noninvasive therapeutic approach that has been applied
in studies for the treatment of various diseases. In this context, PDT has been suggested as …
in studies for the treatment of various diseases. In this context, PDT has been suggested as …
Synthesis and evaluation of novel coumarin-oxime ethers as potential anti-tubercular agents: Their DNA cleavage ability and BSA interaction study
As a contribution to the development of novel coumarin-oxime ether conjugates with
therapeutically interesting properties, a series of coumarin-oxime ether (1a–1j) was …
therapeutically interesting properties, a series of coumarin-oxime ether (1a–1j) was …
Design, synthesis of benzocoumarin-pyrimidine hybrids as novel class of antitubercular agents, their DNA cleavage and X-ray studies
DS Reddy, KM Hosamani… - European Journal of …, 2015 - Elsevier
Abstract A series of 2-(2-(4-fluorobenzyl)-6-(substituted phenyl) pyrimidin-4-yl)-3H-benzo [f]
chromen-3-one derivatives (1a–1o) were selectively prepared in high yields under …
chromen-3-one derivatives (1a–1o) were selectively prepared in high yields under …
Microwave-assisted synthesis of new fluorinated coumarin–pyrimidine hybrids as potent anticancer agents, their DNA cleavage and X-ray crystal studies
An efficient and rapid synthesis of 3-(2-(4-fluorobenzyl)-6-(substituted phenyl) pyrimidin-4-yl)-
2H-chromen-2-one derivatives (1a–1l) under microwave-irradiation has been described in …
2H-chromen-2-one derivatives (1a–1l) under microwave-irradiation has been described in …
Fluorinated isoxazolines and isoxazoles: A synthetic perspective
V Kumar, K Kaur - Journal of Fluorine Chemistry, 2015 - Elsevier
Isoxazoline and isoxazole derivatives are an important class of nitrogen and oxygen
containing heterocycles that are well known to display an array of various biological …
containing heterocycles that are well known to display an array of various biological …