Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

Mesenchymal stem cells (MSCs) have been used in clinic for approximately 20 years.
During this period, various new populations of MSCs have been found or manipulated …

Mesenchymal stem cell secretome or conditioned medium (MSC-CM) is a combination of
biomolecules and growth factors in cell culture growth medium, secreted by mesenchymal …

Bone morphogenetic protein-2 (BMP-2) is a potent growth factor affecting bone formation.
While recombinant human BMP-2 (rhBMP-2) has been commercially available in cases of …

Abstract Background Mesenchymal stem cells (MSCs) are undifferentiated cells that can
give rise to a mesoderm lineage. Adipose-derived MSCs are an easy and accessible source …

Continued improvements in the understanding and application of mesenchymal stem cells
(MSC) have revolutionized tissue engineering. This is particularly true within the field of …

Background The dog represents an excellent large animal model for translational cell-based
studies. Importantly, the properties of canine multipotent stromal cells (cMSCs) and the ideal …

Stem cell spheroids have been studied extensively in organoid culture and therapeutic
transplantation. Herein, hydrogels with an embossed surface (HES) were developed as an …

Adipose tissue represents a hot topic in regenerative medicine because of the tissue source
abundance, the relatively easy retrieval, and the inherent biological properties of …

Introduction: Cell-based therapies exploit the heterogeneous and self-sufficient biological
environment of stem cells to restore, maintain and improve tissue functions. Adipose-derived …